Senior Principal Scientist, Cardiovascular, Translational Development

Position Summary

Translational Development is part of the Global Research organization and leads late‑stage clinical, pharmacological and translational research and development activities for the pipeline. It supports the late‑stage portfolio for regulatory, translational development and life cycle management, driving strategy across core therapeutic areas including hematology, oncology, immunology, cardiovascular and neuroscience. The group integrates laboratory science, clinical trial/biomarkers, asset development and disease research to maximize the potential of BMS’s current and future therapeutics.

• Designs and implements program‑specific development biomarker/translational plans.
• Creates clinical protocols, SAPs, SOWs, lab manuals and interfaces with CROs for service execution.
• Determines appropriate assays and vendors for clinical biomarkers, manages outsourcing of biomarker assay development and validation.
• Manages clinical biomarker data delivery, analysis and associated timelines in collaboration with internal functions and CROs.
• Prepares and delivers internal and external translational/biomarker presentations.
• Maintains timelines for biomarker‑related publication through interaction with Medical Communications and Publication teams.
• Works with TM laboratory scientists and academic TLs to address nonclinical translational questions.
• Participates and leads post‑hoc biomarker analysis and publication efforts.
• Supports regulatory submissions and regulatory interactions as needed.
• Participates in Diagnosis (PDx) biomarker assay development through collaboration with precision‑medicine group.

• PhD with 5–8+ years of translational medicine and clinical biomarker experience, including 5+ years supporting early‑and‑or‑late‑stage clinical programs in biotech or pharma.
• Recognized expertise in translational biomarkers in cardiovascular or related disease areas, with experience in drug development and clinical trial initiation, conduct and completion.
• Experience interacting with CROs and thought leaders to manage projects, timelines and deliverables.
• Demonstrated scientific and project leadership experience, including working in cross‑functional teams, mentoring and managing projects, with the ability to identify risks and implement contingency plans.
• Experience mining and interpreting datasets in collaboration with bioinformaticians to understand mechanism of action, disease pathophysiology or patient segmentation hypotheses.
• Strong communication skills, including preparing and delivering presentations within the department, to governance and senior leadership and externally as needed.
• Ability to support multiple projects in a fast‑paced, collaborative environment, with strong organizational skills, attention to detail and accurate record‑keeping.

Brisbane, CA – $184,060 – $223,036
Cambridge Crossing – $184,060 – $223,036
Princeton, NJ – $160,060 – $193,949

Compensation is based on qualifications, experience and location. Additional incentive cash and stock opportunities may be available based on eligibility.

• Health Coverage:
  Medical, pharmacy, dental and vision care.
• Well‑being Support:
  Wellness programs and Employee Assistance Programs.
• Financial Well‑being and Protection: 401(k) plan, disability and life insurance, supplemental health insurance, travel protection and other safeguards.
• Paid Time Off: US exempt employees have flexible time off with manager approval, 11 paid national holidays; other categories receive specified vacation and holiday schedules.
• Additional time‑off options include unlimited paid sick time, volunteer days, summer hours flexibility and leave of absence for medical, parental and other needs.

BMS is committed to diversity and inclusion and considers qualified applicants with arrest and conviction records as permitted by law.

BMS will never request payments, financial information or social security numbers during recruitment.