Senior Director, Solid Tumor Asset Lead, Translational Development

Position Summary

The Asset Lead role will be responsible for development and execution of translational strategies in solid tumor oncology for assigned programs. Key responsibilities include leading translation/biomarker plans, developing and delivering innovative biomarker strategies, generating reports and publications, supporting regulatory submissions, and engaging internal and external stakeholders.

• Integrate translational research and clinical development, developing biomarker strategies in alignment with clinical objectives, leading data generation and interpretation and communication to development teams.
• Responsible for understanding external research environment, partnering with other functions internally and externally to coordinate execution of translational development deliverables.
• Engage functional groups to develop, champion, implement and align biomarker strategies for development projects in support of R&D portfolio goals.
• Effectively engage with teams and matrix leadership to define, revise and progress translational biomarker plans.
• Continually analyze progress, engage in critical thinking and assert strong problem‑solving toward delivering key data and interpretations essential for decision making.
• Deliver high‑quality biomarker strategies for understanding mechanism of action/resistance, target engagement, pharmacodynamics endpoints and patient selection.
• Ensure the output of the biomarker plans meets established project standards.
• Engage team members to ensure alignment of biomarker strategies with clinical operational plans and functional capabilities.
• Build productive relationships with team members that interact with the translational clinical biomarker group.
• Effectively interface with functional areas to ensure strategic alignment and identify resources needed to deliver on biomarker goals.
• Communicate key biomarker program information, risks, milestones, and manage information flow across team members.

• Ph.D. in Oncology/Hematology or related field with 12+ years of industry experience, including significant time in translational capacity.
• Comprehensive knowledge of principles, concepts and methodologies within drug discovery or clinical development.
• Significant understanding of the role of translational research/medicine and clinical biomarkers in drug development.
• Demonstrated knowledge of oncology and/or tumor‑immunology disease biology.
• Strong understanding of modality‑agnostic therapies, including small molecules and biologics.
• In‑depth understanding of solid tumor oncology with knowledge of current and evolving clinical landscape; therapeutic area experience a plus.
• Strong scientific background with demonstrated impact using clinical, translational, and mechanistic data.
• In‑depth understanding of early or late‑stage drug and translational development process with proven track record of successful implementation of biomarker strategy.
• Clinical protocol authoring and review of regulatory documents.
• Working knowledge of technological platforms covering biomarker measures including genomics, gene expression, immune profiling, and flow cytometry.
• Excellent data analysis and problem‑solving skills.
• Exceptional verbal and written communication skills with experience in developing manuscripts, publications, scientific presentations and regulatory submissions, with ability to synthesize complex scientific concepts into simple communication points.
• Proven track record of writing and publishing scientific articles as major contributor.
• Proven scientific/project leadership expertise and experience working on complex global teams, managing people/projects and leading external collaborations.
• Experience interacting with health authorities.
• Ability to influence internal and external stakeholders across the business continuum.

• Health Coverage:
  Medical, pharmacy, dental and vision care.
• Well‑being support programs including BMS Well‑Being Account, BMS Living Life Better and Employee Assistance Programs.
• Financial well‑being and protection: 401(k) plan, disability insurance, life insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support and survivor support.

Job Title:

Senior Director, Solid Tumor Asset Lead, Translational Development (R1601801)