Assoc Prin. Scientist, Analytical R&D

Job Description

The Materials & Biophysical Characterization (MBC) group within Pharmaceutical Analysis & Digital Technologies is seeking a highly motivated and technically focused individual interested in positively impacting our Company's pipeline from discovery through development and commercial launch. This position is for a Pharmaceutical Materials Scientist to be a key member of a team responsible for the physicochemical characterization of pharmaceutical materials including small molecule active pharmaceutical ingredients (API), chemical intermediates, peptides, novel excipients, drug-product intermediates, and drug products.

The candidate will utilize their expertise in physical organic chemistry or materials science as a member of cross-functional teams to tackle scientific challenges related to crystallization, polymorph and salt-selection, drug-excipient compatibility, characterization of amorphous solid dispersions, and physical stability of API and drug products. Additional expectations include building a strong network internally and across the external academic and regulatory community. The selected candidate will advance a culture of scientific excellence, a compliance mindset, and collaboration with partners and stakeholders across our Company's network such as Discovery Chemistry, Process & Analytical Chemistry, Chemical Engineering and Formulations Sciences.

• Bachelors or Masters degree in Materials Science and Engineering, Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline, with a minimum of eight (8) years relevant industrial experience (non-academic) OR PhD in Materials Science and Engineering, Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline with 4 years relevant industrial experience (non-academic).

• Expertise in materials science or physical chemistry with experience in materials characterization techniques such as X‑ray diffraction, thermal analysis, electron microscopy, vibrational spectroscopy, particle size analysis or powder property characterization.
• Strong academic record including publications in peer reviewed journals and presentations at scientific meetings.
• Self‑motivated, creative and energetic scientist willing to continually learn and solve complex problems.
• Strong written and verbal communications.

• Active pharmaceutical ingredient (API) polymorph screening and crystallization.
• Amorphous solid dispersion characterization.
• Modified release dosage forms.
• Automation and data science.
• Late‑stage product development and regulatory documentation / filing.
• API polymorph screening and crystallization.
• Amorphous solid dispersion characterization.
• Modified release dosage forms.
• Automation and data science.
• Late‑stage product development and regulatory documentation / filing.

• Analytical Chemistry
• Analytical Method Development
• Assay Development
• Biological Assay Development
• Cell‑Based Assays
• Chemical Engineering
• Chromatographic Techniques
• Crystallizations
• High Resolution Mass Spectrometry (HRMS)
• Liquid Chromatography‑Mass Spectrometry (LC‑MS)
• Mass Spectrometry Analysis
• Pharmaceutical Sciences
• Process Analytical Technology (PAT)
• Protein Analysis

• Automation and data science
• Advanced scripting and programming skills
• Statistical analysis
• Integrated data analysis and visualization
• Data mining
• Data modeling
• Statistical tools
• Software such as R, Python, SQL, SAS, etc.
• Data science fundamentals
• In‑house software development and programming
• Use of distributed computing framework (Spark, Hadoop)
• Cloud technologies and data engineering
• API development and deployment
• AI/ML concept and implementation
• Deep learning

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected…