Scientist - II; Associate

Job Title

Qualifications

• BA/BS (6 yrs.) of relevant experience in analytical chemistry or biologics testing lab
• MS (4 yrs.) of relevant experience in analytical chemistry or biologics testing lab
• Ph.D. (1-2 yrs.) of relevant experience in analytical chemistry or biologics testing lab Required Skills and Experience
• Must have separations experience for large molecules or plate-based assay experience.
• Experience in analyzing biologics including monoclonal antibodies and/or other therapeutic proteins using at least one of the following techniques: o Liquid Chromatography (HPLC / UPLC) o Protein A Titer, Size Exclusion Chromatography (SEC), Ion Exchange Chromatography (IEX, AEX, CEX), Reverse Phase (RP), or Hydrophobic interaction chromatography (HIC) o Electrophoretic methods such as capillary electrophoresis sodium dodecyl sulfate (CE-SDS) and/or capillary isoelectric focusing (cIEF)
• Basic instrumentation troubleshooting
• Ability and willingness to train and follow laboratory methods and procedures
• Familiarity with Microsoft Office Applications (Outlook, Excel, Word, PowerPoint, One Note, Teams, etc.)
• Making accurate reagent preparations (dilutions / solutions / buffers / mobile phases)
• Good documentation practices & utilization in electronic lab notebooks (ELN) Desired Skills and Experience
• Analytical software such as Empower.
• Experience in analyzing biologics including monoclonal antibodies and/or other therapeutic proteins using plate-based methods, e.g., ELISA (HCP, proA)
• Familiarity with compendial testing such as UV 280, pH, and Physical Observations Notes:
• Open to bachelor, masters, and/or PhD level.
• 100% onsite lab based role.
• Required to have direct expertise in operating LC and CE analytical systems for testing large molecules in an industry or CRO environment.
• Required to be experienced in the industry, with ability to quickly train on Merck-specific procedures and start working in the lab.
• Role will involve high volume sample testing across multiple preclinical and clinical stage biologics programs, including proteins and antibody-drug conjugates.
• Required to follow all safety, compliance and quality practices.
• Required to understand and follow good documentation practices within an electronic laboratory notebook.
• Required to have strong communication skills, ability to collaborate, and ability to work independently.

Description Support of routine Biologics analytical testing of samples from cell-line development, in-process, process development/characterization, forced degradation, release & stability, and pre-formulation.

Responsibilities
• Support of high-throughput, pre-formulation, pre-qualification, robustness, or admixture testing
• Results processing and documentation by following appropriate methods / protocols / procedures
• Sample management and monitoring of controlled temperature units.
• Following all appropriate laboratory safety and hygiene procedures.