Senior Principal Scientist, Clinical Research, Breast Cancer

Job Overview

The Senior Director (Sr. Principal Scientist) is responsible for planning and directing clinical research activities involving new or marketed oncology medicines across all phases of clinical development.

• Evaluate pre‑clinical and translational work to generate early clinical development plans and Investigational New Drug applications.
• Develop clinical development strategies for investigational or marketed oncology drugs.
• Plan clinical trials (design, operational plans, settings) based on development strategies.
• Monitor and manage the conduct of ongoing or new clinical trials for investigational or marketed oncology drugs.
• Analyze and summarize clinical findings to support decisions on safety, efficacy, regulatory submissions, study reports, and publications.
• Participate in internal and joint research project teams relevant to new compound development and further study of marketed compounds.
• Supervise clinical scientists executing clinical studies.
• Work closely with a cross‑functional team of experts in commercialization, regulatory affairs, statistics, and manufacturing to manage clinical development projects.
• Assist executive directors in ensuring that corporate personnel are informed of study progress and scientific questions relevant to responsibilities.
• Maintain awareness of scientific developments within the area of expertise, identify strong investigators, and establish communications with prominent clinical investigators.
• Attend scientific meetings to maintain competency and awareness of research activities.
• Author detailed development documents, presentations, budgets, and position papers for internal and external audiences.
• Facilitate collaborations with external researchers worldwide.
• Travel on company business approximately 25% of the time to manage future or ongoing clinical research projects.

• M.D. or M.D./Ph.D.

• Experience in industry or senior faculty in academia.
• Minimum of 3 years of clinical medicine experience.
• Minimum of 1 year of industry experience in drug development or biomedical research in academia.
• Demonstrated record of scientific scholarship and achievement.
• Proven track record in clinical medicine and background in biomedical research.
• Strong interpersonal skills and ability to function in a team environment.

• Board Certified or Eligible in Oncology (and/or Hematology).
• Prior specific experience in clinical research and prior publication.

• Breast Cancer
• Clinical Development
• Clinical Medicine
• Clinical Research Management
• Clinical Trials
• Data Analysis
• Decision Making
• Drug Development
• Ethical Standards
• Oncology Research
• Oncology Trials
• Scientific Publications
• Strategic Planning

Current employees and contingent workers can apply through the company’s internal portals.

Salary range: $ – $, based on education, qualifications, experience, and other factors. Successful candidates may be eligible for annual bonus and long‑term incentive, if applicable.

Benefits include medical, dental, vision, retirement (401(k)), paid holidays, vacation, compassionate and sick days, and other insurance benefits. Further information is available at the company’s benefits website.

As an Equal Employment Opportunity Employer, we provide equal opportunities for all employees and applicants. Discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics is prohibited. We comply with all federal affirmative action requirements for protected veterans and individuals with disabilities. For more information on personal rights under U.S. Employment laws, please refer to the relevant EEOC resources.