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Senior Scientist, Biocatalysis

Job in Rahway, Union County, New Jersey, 07065, USA
Listing for: Merck & Co.
Full Time position
Listed on 2026-07-15
Job specializations:
  • Research/Development
    Biotech Research, Research Scientist, Drug Discovery
Salary/Wage Range or Industry Benchmark: 117000 - 184200 USD Yearly USD 117000.00 184200.00 YEAR
Job Description & How to Apply Below

Senior Scientist – Biocatalysis, Small Molecule Process R&D, Rahway, New Jersey

Job Summary

The Biocatalysis group is seeking a Senior Scientist to design and deliver world‑class biocatalytic solutions that enable the development of medicines. The role focuses on inventing, developing, and implementing novel enzymes, biocatalytic reactions, and synthetic processes to support drug discovery, clinical supply, and commercial manufacturing. The interdisciplinary team integrates biosynthetic logic, mechanistic investigation, data‑rich experimentation, molecular biology, biochemistry, bioinformatics, and advanced automation to drive innovation in drug discovery and development.

Responsibilities
  • Lead the invention, development, and implementation of novel enzymes, biocatalytic reactions, and synthetic processes.
  • Develop scalable biocatalytic routes for drug development in multidisciplinary project teams.
  • Design and execute experiments and propose novel approaches to challenging scientific problems.
  • Present scientific findings internally and externally; contribute to publications and patents.
  • Define scientific strategy for programs and accelerate R&D in enzyme engineering and biocatalysis.
Education Requirements
  • Ph.D. or Postdoctoral Education in Chemistry, Biochemistry, Bioengineering, Biophysics, Chemical Engineering, Molecular Biology, Synthetic Biology, or a related field;
  • M.S. with at least 4 years of relevant industry experience;
  • B.S. with at least 5 years of relevant industry experience.
Required Experience and Skills
  • Demonstrated scientific accomplishments in biocatalysis, enzyme engineering, or a related field with impact‑making research publications.
  • Deep expertise in biocatalysis or enzyme engineering with proven problem‑solving ability.
  • Track record of solving complex scientific problems in collaborative, multidisciplinary teams.
  • Excellent communication and organizational skills.
Preferred Experience and Skills
  • Experience in developing biocatalytic or chemoenzymatic syntheses.
  • Experience with multiple strategies to identify and engineer enzymes for biocatalytic use.
  • Experience engineering novel biocatalysts, biosynthetic pathways, or de‑novo proteins.
  • Familiarity with directed evolution, next‑generation sequencing, computational protein design, machine learning, microfluidics, analytical chemistry, chemical engineering, or laboratory automation.
  • Proficiency in reproducible data analysis using Python or R.
Additional Information
  • Salary: $117,000 – $184,200 (base)
  • Potential eligibility for annual bonus and long‑term incentive.
  • Benefits include medical, dental, vision, retirement (401(k)), paid holidays, vacation, and sick days.
  • Travel requirement: 10%
  • Domestic relocation support.
  • VISA sponsorship available.
Eligibility
  • US and Puerto Rico residents only.
  • San Francisco and Los Angeles residents may apply under local fair‑chance ordinances.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. We comply with affirmative action requirements for protected veterans and individuals with disabilities.

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Position Requirements
10+ Years work experience
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