Associate Principal Scientist, Clinical Research

Associate Principal Scientist, Clinical Research Skip to main content
* This site uses cookies to provide you with an optimal user experience. The cookies include Strictly Necessary and Functional cookies to ensure the site operates as intended (language preference, time zone and workload balance). These cookies are first party cookies, end with the session and are exempted from consent. In addition, this site also uses a Google Analytics Cookie to measure and improve the performance of our site.

All information these cookies collect is aggregated and therefore anonymous. By clicking on the ‘Accept Cookies’ button, you are accepting this Performance cookie.  You may use this site if you click on the ‘Reject Cookies’ button. To revoke your consent of the Performance cookie, clear your cookies within your browser settings.*#Associate Principal Scientist, Clinical Research page is loaded## Associate Principal Scientist, Clinical Research Apply remote type:
Hybrid locations:
USA
- Pennsylvania
- West Point:
USA
- Massachusetts
- Boston (MA Parcel B Laboratory):
USA
- California
- South San Francisco (Gateway Blvd):
USA
- New Jersey
- Rahway:
BEL
- Brussels
- Brussels (Souverain) time type:
Full time posted on:
Posted Todaytime left to apply:
End Date:
July 15, 2026 (20 days left to apply) job requisition :
R403573
** Job Description
** Translational Medicine (TMed) drives early clinical development of novel therapeutics by partnering with Discovery Sciences and Late-Stage Clinical Research to translate scientific discoveries into human proof-of-concept and advance the most promising candidates through the pipeline to patients. We design and execute clinical pharmacology strategies spanning first-in-human studies through proof-of-biology/proof-of-concept and into late-stage development, supporting worldwide marketing applications and lifecycle management.

The Early Clinical Scientist (ECS) provides operational and scientific leadership, along with therapeutic expertise, for the design, planning, and execution of early-phase clinical trials and programs in collaboration with the Clinical Director and cross-functional teams. Accountable for the oversight, strategic direction, and execution of Immunology programs including multiple Phase 1 and 1b trials across programs and developmental stages. Manages cross-functional team performance to achieve trial objectives and addresses issues if they arise.

Ensures execution excellence and compliance with GCP, ICH, and regulatory requirements, supporting study objectives and the delivery of high-quality data.

Ensures appropriate clinical safety assessment and risk management of compounds, and provides real-time oversight of ongoing trials to identify and mitigate participant, study design, data, or study conduct issues. Reviews and interprets clinical trial data and may participate in on-site study monitoring, including site training & supervision of complex, novel endpoint/biomarker collection processes. Represents Early Stage Development on early development and product development teams.

Leads the development of departmental job aids/SOPs and participates in, or leads, cross-functional teams developing global clinical development procedures. Identifies and communicates best practices across the organization. Promotes departmental adaptation of new procedures and builds junior team members’ capabilities through proactive coaching, mentoring, and development opportunities. May represent the company at professional events. present clinical initiatives, projects, and/or clinical trial results.

Technical Writing & Communications Responsible for authoring clinical protocols, investigator brochures, clinical study reports, health authority update reports, responses to regulatory agencies and audits/inspections, and other clinical and regulatory documents. Authors and coordinates the development of WMA/CTD subsections. Assist Clinical Directors with scientific leadership and investigator initiatives, including publications, meeting presentations, and due diligence activities. Ensures documents are completed in accordance with applicable standards.

Develops study operational documents…