Scientific AVP, Clinical Research, Oncology Early Development

Job Summary

We are searching for a Section Lead to join Oncology Early Development (OED) to oversee clinical strategy for early development pipeline and lead cross‑functional teams.

• Strategic Leadership: oversee early pipeline assets including IO targets, ADCs, TCEs and small molecules; mentor reports; represent programs in senior management forums.
• Clinical Development Plan (CDP): develop and execute end‑to‑end clinical plans, including Phase 1/2 trial design, IND submissions, and Investigator Brochures.
• Cross‑functional
  
  Collaboration:
  
  partner with Discovery, Translational Medicine, Clinical Pharmacology, Regulatory, and Operations teams to ensure fast and effective trial execution.
• Scientific & Medical Expertise: analyze patient data, PK/PD modeling and biomarkers to optimize dosing and compound strategy.
• Talent Management: mentor and provide feedback to clinical team members and scientists to build high‑performing teams.
• External Outreach and Leadership: stay abreast of industry trends and emerging technology through conferences, literature, and training.

• MD, MD/PhD with a strong background in oncology and early drug development.
• 10+ years of industry experience, including at least 5 years in oncology early development.
• In‑depth knowledge of early development/Phase 1 clinical trial methodology, regulatory and compliance requirements, and design of study protocols.
• Strong scientific background in oncology drug development (basic, translational, and/or clinical) and experience with multiple mechanisms of action (small molecules, biologics including ADCs and TCEs).
• Proven leadership skills and ability to influence cross‑functional global teams.
• Excellent oral and written communication skills.

• Change Management
• Clinical Pharmacology
• Clinical Strategy
• Clinical Trial Development
• Consulting
• Ethical Standards
• Executive Presence
• Immunology
• Innovation
• Interpersonal Relationships
• Results‑Oriented
• Translational Medicine
• Vaccine Development

Salary range: $ – $. Eligible for annual bonus and long‑term incentive, if applicable. Comprehensive benefits include medical, dental, vision, healthcare, retirement benefits (401(k)), paid holidays, vacation, compassionate and sick days, and other insurance benefits.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. We are a federal contractor and comply with affirmative action requirements for protected veterans and individuals with disabilities.