Senior Specialist, Quantitative Pharmacology and Pharmacometrics - Immuno-Oncology; QP‑IO

Job Title

Senior Scientist, Quantitative Pharmacology and Pharmacometrics – Immune/Oncology (QP2-IO)

The Quantitative Pharmacology and Pharmacometrics – Immune/Oncology (QP2-IO) Department seeks a Senior Scientist to support our oncology pipelines. The role involves quantitative modeling to inform drug discovery and development, collaborating across cross‑functional teams and with external partners.

• Develop model‑based strategies (translational PK/PD, mechanistic models, POPPK/PD, clinical trial simulations) across programs to support dose selection, trial design, and go/no‑go decisions.
• Represent QP2-IO on oncology discovery, early and late clinical development teams, leveraging quantitative approaches.
• Collaborate with functional areas and external vendors on study design, protocol development, study execution, reporting, and data interpretation.

• Minimum Education:
  
  Ph.D. with 0‑2 years experience; or PharmD/MS/related degree with 2‑4 years of relevant experience and increasing responsibility.
• Educational background in biopharmaceutics, pharmaceutical sciences, pharmacometrics, chemical/biomedical engineering, or related field.
• Experience performing population PK, PK/PD analyses using standard pharmacometrics software (NONMEM, Monolix, Phoenix, etc.).
• Strong written and verbal communication, interdisciplinary collaboration, and problem scoping and planning skills.

• Knowledge of oncology clinical drug development programs.
• Skills in experimental design, mathematical problem solving, critical data analysis/interpretation, and statistics.
• Scientific understanding of biopharmaceutical and ADME properties of small molecules and/or biologics.

United States (remote/hybrid). Remote allowed for candidates not within commutable distance to primary site; expected commute less than 50 miles if hybrid.

Salary range: $ – $ (based on education, qualifications, experience, location, and business needs). Eligible for annual bonus and long‑term incentive. Comprehensive benefits package includes medical, dental, vision, retirement with 401(k), paid holidays, vacation, and sick days.

We are an Equal Employment Opportunity Employer and provide equal opportunities to all employees and applicants for employment. We prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics. For more information, see the EEOC resources.