Senior Specialist, Quantitative Pharmacology and Pharmacometrics – Immuno-Oncology; QP‑IO

Role Overview

• Senior Scientist (Quantitative Pharmacology and Pharmacometrics – Immune/Oncology, QP2-IO) supporting oncology pipelines.

• Contribute to model-based strategies (translational PK/PD, mechanistic models, POPPK/PD, clinical trial simulations) to support quantitative analyses across programs to inform and optimize drug discovery and all phases of development (dose selection, trial design, go/no-go decisions).
• Represent QP2-IO on oncology discovery, early clinical development, and late clinical development teams using quantitative approaches to streamline programs.
• Collaborate with functional areas and external partners/vendors on study design, protocol development, execution, and reporting/interpretation of data.

• Ph.D. with 0–2 years experience; OR
• PharmD or MS or equivalent with preferably 2–4 years of relevant experience (increasing responsibility/independence in drug development, regulatory agency, or academia).

• Background in biopharmaceutics/pharmaceutical sciences/pharmacometrics/chemical or biomedical engineering (or related).
• Experience performing population PK and PK/PD analyses using software such as NONMEM, Monolix, or Phoenix.
• Strong written/verbal communication; interdisciplinary collaboration; problem scoping and planning.

• Oncology clinical drug development program knowledge.
• Experimental design, mathematical problem solving, critical data analysis/interpretation, and statistics.
• Understanding of biopharmaceutical and ADME properties of small molecules and/or biologics.

• Communication, Data Modeling, Data Visualization, Drug Development, Model Development, Modeling Software, Pharmacometrics.

• ADME, Biologics, Biopharmaceutical Research, Biopharmaceuticals, Clinical Development, Clinical Trial Designs.