Research Associate II​/Senior Research Associate Upstream

Syst Immune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi‑specific, multi‑specific antibodies, and antibody‑drug conjugates (ADCs). Syst Immune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials, Syst Immune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND‑enabling stages, representing cutting‑edge biologics development.

We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.

We are seeking a highly skilled and motivated Upstream RAII or Sr. Research Associate to join our team onsite in Redmond, WA. This individual will lead and execute upstream project process development (USP) and technology transfer activities to support the development of clinical manufacturing processes for our protein therapeutics pipeline. The ideal candidate will have hands‑on experience with mammalian cell culture, bioreactor operations, and process scale‑up for biologics production.

• Design, plan and execute experiments in shake flasks, bench‑top bioreactors, and other appropriate scale‑down equipment in the development laboratory
• Ensures timely, effective, and high‑quality documentation in electronic laboratory notebooks and internal technical reports
• Share results with stakeholders and present data to colleagues, management, and external audiences through project meetings, technical reviews, and conferences
• Support the technology transfer of manufacturing processes to pilot, clinical, and commercial facilities
• Provide support and troubleshoot during manufacturing campaigns as needed
• Collaborate with team members and cross‑functional groups to support safe, efficient, and well‑organized lab operations

• BS/BA with 2+ years of experience, or MS with 1+ years of experience in Biotechnology, Microbiology, Cell Biology, Chemical/Biochemical Engineering, or other related disciplines
• Relevant research experience in a laboratory setting
• Basic understanding of mammalian cell culture
• CHO cell culture experience preferred
• Bioreactor setup and operation experience is strongly preferred
• Ability to grasp scientific concepts, interpret complex data, and formulate new hypothesis
• Requires competency in aseptic laboratory technique and the ability to design and carry out complex experiments and interpret data
• Requires demonstrated effectiveness in collaborative projects, and ability to communicate effectively with scientists and management in a highly matrixed organization
• Ability to lift 30 lbs (cell culture media/buffer bags)
• Occasional weekend work will be required
• Work Location Assignment:
  On Premise

• Practical knowledge and/or experience with microbial/mammalian cell culture metabolism, scale up, GLP/GMP practices, and technology transfers to pilot/commercial sites
• Team oriented, with excellent oral and written communication skills
• Well organized and great attention to detail

This job description is intended to present the general content and requirements for this job. The description is not to be construed as an exhaustive statement of duties, responsibilities, or requirements. Managers and supervisors may assign other duties as needed.

The expected base salary range for this position is $60,000 - $85,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience, and skills. While most offers typically fall within the low to mid‑point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise align strongly with the requirements of the role.

• 100% paid employee premiums for medical/dental/vision
• STD and LTD
• 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years
• 15 PTO days per year
• Sick leave
• 11 paid holidays
• and MORE

Syst Immune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.