Senior Scientist, Cell Science

The Senior Scientist in the Cell Science Department is responsible for the development and optimization of CHO-based processes for the production of biotherapeutics.

This position requires a full-time onsite presence at our Redmond, WA location.

• Design and execute cell line development workflows, including vector design, transfection, clone screening, and selection for stable expression.
• Perform cell culture experiments involving mammalian cells (e.g., CHO cells) under sterile, aseptic conditions.
• Develop and optimize expression systems, including promoters, selection markers, and gene amplification strategies for high-yield production.
• Screen and characterize clones for productivity, stability, growth characteristics, and product quality attributes using molecular and biochemical assays.
• Collaborate with project teams and downstream process development scientists to execute protocols, experimental plans, critical production batches, and technology transfers.
• Manage and prioritize multiple projects while supporting and coordinating with other departments to advance company objectives and develop scalable, robust culture processes.
• Write and review Standard Operating Procedures (SOPs) and technical reports for regulatory filings.
• Prepare process transfer documents and cGMP documentation to support the successful implementation of process technologies in clinical and commercial manufacturing operations.
• Collaborate with R&D and the manufacturing team in China, participating in meetings and providing technical support as needed.
• Availability to work weekend and holiday shifts, as required.
• Perform other duties as assigned.

• Ph.D. in Cell Biology or a related field, with 5+ years of relevant experience in the pharmaceutical or biotechnology industry.
• Strong scientific background in recombinant protein expression, cell line development, cellular metabolism, and media optimization.
• Experience in both early- and late-stage bioreactor operations, mammalian stable cell line development, and upstream process development is preferred.
• Demonstrated expertise in advanced technologies for cell line development, with a focus on antibody production.
• Strong knowledge of FDA regulations and other global health authority requirements related to Investigational New Drug (IND) applications, particularly those concerning single stable clone selection and characterization.
• Excellent written, verbal, and interpersonal communication skills.
• Proven ability to perform effectively under pressure, meet tight deadlines, and adapt to shifting project priorities and requirements.
• Experience with high-throughput automated workstations for clone selection is highly desirable.

• The expected base salary range for this position is $90,000 - $140,000 annually.
• Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience, and skills.
• We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.

• 100% paid employee premiums for medical, dental, and vision coverage, as well as STD and LTD.
• 401(k) plan with 50% company match up to 3% and a vesting schedule of 5 years.
• 15 paid time off days per year and sick leave.
• 11 paid holidays.

Syst Immune is an Equal Opportunity Employer.

We welcome diverse talent and encourage all qualified applicants to apply.