Scientist, Immuno-Oncology

Syst Immune is a leading and well‑funded clinical‑stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi‑specific, multi‑specific antibodies, and antibody‑drug conjugates (ADCs). Syst Immune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. Syst Immune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND‑enabling stages, representing cutting‑edge biologics development.

We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

This on‑site role is within the Immuno‑Oncology Research and Development group. We are seeking a highly motivated Scientist with a strong experimental background in cellular and molecular biology, immunology, and assay development. The successful candidate will support discovery‑stage programs through execution of in vitro experiments, immune cell‑based assays, sample preparation, and advanced imaging workflows. The ideal candidate will have a PhD and hands‑on laboratory experience in immunology, cell biology, or a related discipline, with an interest in learning and applying microscopy‑based approaches to support therapeutic antibody discovery and characterization.

• Design, execute, and analyze cellular and immunological assays supporting antibody and multi‑specific therapeutic programs
• Perform mammalian cell culture, immune cell isolation, immune phenotyping, and functional characterization assays
• Support sample preparation and execution of microscopy‑based experiments, including fluorescence imaging and other advanced imaging platforms
• Assist in development, optimization, and troubleshooting of in‑vitro assays for therapeutic molecule evaluation
• Generate, analyze, and interpret experimental data using appropriate statistical and visualization tools
• Present findings at internal team meetings and contribute to scientific discussions
• Maintain detailed laboratory records and prepare written summaries of experimental results
• Collaborate closely with scientists across immunology, protein engineering, bioassays, and computational biology teams
• Contribute to establishment of new experimental methods and workflows as programs evolve
• Other duties as assigned

• PhD in Immunology, Cell Biology, Cancer Biology, Molecular Biology, Bioengineering, or a related field
• Strong hands‑on experience with mammalian cell culture and cell‑based assays
• Working knowledge of immunology and immune cell biology
• Experience with fluorescence microscopy, image analysis, or sample preparation for imaging applications is highly desirable
• Experience with flow cytometry, immune phenotyping, or functional immune assays preferred
• Demonstrated ability to learn new technologies and experimental techniques quickly
• Strong analytical, organizational, and problem‑solving skills
• Excellent written and verbal communication skills
• Collaborative mindset with a positive, adaptable, and proactive approach to research
• Possess the right attitude (agile, curious, positive, open‑minded, “can‑do” mindset), and have the ability and strong desire to “make things happen”

• Bench top work in a BSL‑2 laboratory environment, including potential exposure to biohazards
• Adherence to Health and Safety standards when working with temperature‑controlled systems, including liquid and vapor phase liquid nitrogen

• Occasional lifting to 30 pounds
• Requires repetitive multi‑channel pipetting, single‑channel pipetting, and computer data entry
• Fine motor movements in fingers/hands to operate computers and other office and lab equipment, repetitive motion with lab equipment
• Stooping, bending, crouching, reaching, or climbing ladders

• May need to work outside of standard working hours at times
• This role is currently working onsite and is expected to work onsite for working hours, with flexibility to work start time. The work location for this role is in Redmond,…