Senior Scientist, Immuno-Oncology

Syst Immune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). Syst Immune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. Syst Immune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development.

We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

This Senior Scientist role isin the research anddevelopmentdivision.

Candidates with a passion for agentic AI-based system development are highly encouraged to apply.

This role is full-time onsite at our Redmond, WA location and we will be moving to our new building in Bothell, WA fall 2026.

• Establish and applyin vitro, andin situmodels toidentifyandcharacterize novelantibodytherapeutics
• Evaluate novel pathways and mechanisms for immunological therapeutic intervention and formulate strategies for bispecific andtherapeuticcombination approaches
• Work as part of highly collaborative interdisciplinary team
• Prepare written reportsto specification and oral presentations on research projects
• Prepare documents for submission to domestic and international regulatory agencies
• Lead immuno-oncologydiscovery/preclinical projects
• Other duties as assigned

• PhDinimmunology,cancerbiologyor related field with2 - 5+ yearsof relevant academic and/or pharmaceutical or biotech experience
• Background inhumanimmunecell biology, orimmunecellreceptorsignalingresearch
• Expertise in discovery and development ofproteintherapeuticsand mammalian cell culture
• Research experienceindevelopingbispecific antibodiesispreferred
• Excellent time management and organizational skills
• Excellent written,oral,and interpersonal communication skills
• Possess the right attitude (agile, curious, positive, open-minded, “can-do” mindset), and have the ability andstrong desireto “make things happen”

• Bench top work in a BSL-2 laboratory environment, including potential exposure to biohazards
• Adherence to Health and Safety standards when working withtemperature-controlledsystems, including liquid and vapor phase liquid nitrogen

• Occasional lifting to 30 pounds
• Requires repetitive multi-channel pipetting, single channel pipetting, and computer data entry
• Fine motor movements in fingers/hands tooperatecomputers and other office and lab equipment, repetitive motion with lab equipment
• Stooping, bending, crouching, reaching, or climbing ladders

• May need to work outside of standard working hours at times
• This role is currently working onsite and is expected to work onsite for working hours, with flexibility to work start time. The work location for this role is in Redmond,WA

• Attendance and participation in national and international conferences encouraged

The expected base salary range for this position is $90,000 - $140,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills.

• Syst Immune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.

We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.

Syst Immune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.