Scientist II

Responsibilities

• Independently initiates and completes routine in vivo studies efficiently, with minimal supervision. Interprets experimental outcomes and recommends appropriate follow‑up.
• Demonstrates technical proficiency supporting the development and validation of rodent models for cardiometabolic diseases, with an emphasis on kidney disease, under supervision. Experience with cardiovascular rodent models is a plus.
• Applies basic scientific principles with minimal guidance; performs literature searches and extracts relevant information from published protocols.
• Proposes new ideas and technologies, builds support, and implements improvements based on scientific and technical expertise and an understanding of the drug discovery and development process.
• Independently operates and maintains laboratory equipment and troubleshoots issues effectively.
• Communicates work effectively, both orally and in writing; contributes to protocols, procedures, and technical reports; and provides input for scientific reports.
• Records, analyzes, and reports data with a high level of integrity and ethical conduct.
• Complies with applicable regulations and performs all work safely; maintains accurate records in accordance with Standard Operating Procedures and policies.
• Applies knowledge of CKD theory and core scientific principles to conduct in vivo research; direct experience with rodent models of CKD is highly desirable.
• Demonstrates experience with rodent handling, including oral, IP, SC, and IV dosing; blood sampling; health monitoring; and tissue/sample collection.
• Requires moderate physical activity to perform work in the vivarium and laboratory, including standing for extended durations, working under a biosafety hood for extended durations, bending, lifting (up to 20 lbs), squatting, pushing/pulling, and reaching. Also requires daily handling and restraint of small laboratory animals (rats, mice; >50 at a time), often within a specified timeframe.
• Requires use of personal protective equipment (PPE), including respiratory, eye, hand, and foot protection.
• Proven ability to develop, execute, troubleshoot, optimize, and interpret in vivo pharmacology models; experience dosing test articles and working in renal‑related disease areas (e.g., primary glomerulonephritis or cardio‑renal metabolism) is a plus.
• Assists with incorporating new technologies to enhance CKD research. Contributes to the design, execution, and interpretation of non‑routine experiments with minimal supervision and supports implementation of experimental approaches that advance department goals.
• Demonstrates scientific curiosity and strong problem‑solving and troubleshooting skills.
• Knowledge of scientific and technical communication through protocols, procedures, technical reports, and scientific reports.
• Ability and willingness to work effectively in a highly collaborative environment and support weekend work as needed.

Master’s Degree with 0 years experience or Bachelor’s Degree with 3+ years experience in a related scientific discipline; pharmaceutical, biotechnology or CRO experience is highly desirable; non‑PhD applicant required.