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AI​/ML Engineer - Validation & Evaluation

Job in Rochester, Olmsted County, Minnesota, 55905, USA
Listing for: Mayo Foundation for Medical Education and Research
Full Time position
Listed on 2026-09-10
Job specializations:
  • Business
    AI Evaluation
Salary/Wage Range or Industry Benchmark: 116043 - 168293 USD Yearly USD 116043.00 168293.00 YEAR
Job Description & How to Apply Below

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans– to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits

Highlights
  • Medical:

    Multiple plan options.
  • Dental:

    Delta Dental or reimbursement account for flexible coverage.
  • Vision:

    Affordable plan with national network.
  • Pre-Tax Savings:

    HSA and FSAs for eligible expenses.
  • Retirement:
    Competitive retirement package to secure your future.
Responsibilities

AI/ML Engineers at AI Validation & Monitoring (AVM) apply data, systems, computer science, clinical workflow, and governance expertise to help ensure that clinical AI products are supported by proportionate, traceable, and technically sound validation evidence. They work with AIA Governance Operations, clinicians, product teams, human-factors and user-experience specialists, data scientists, IT, architecture, patient safety, legal and regulatory partners, vendors, and other stakeholders to translate AIA Governance Policy and approved validation methods into clear evidence expectations and review conclusions.

As the AI/ML Engineer - Validation & Evaluation, with the functional assignment of Validation Guidance, Guardrails, and Test Evidence, you will perform routine and moderately complex subject-matter review of the Validation, Performance, and Safety content and supporting evidence prepared. You will apply approved rubrics, evidence-sufficiency criteria, checklists, templates, and standard methods; identify missing evidence, unsupported conclusions, methodological limitations, and inconsistencies; document corrections, clarification questions, limitations, and escalation triggers;

and draft traceable AVM concurrence or consultation comments. High-risk, novel, disputed, exceptional, or out-of-method questions are escalated to the Senior or Principal AI/ML Engineer comparisons, residual risk, and whether assessment conclusions are supported by the available evidence.

  • Reviewing validation strategy and pathway selection, including retrospective analysis, prospective testing, simulation, user acceptance testing, human-factors evaluation, pilots, and other risk-proportionate methods, for alignment with intended use, workflow, and patient-safety risk.
  • Evaluating performance expectations, metrics, thresholds, acceptance criteria, standard-of-practice
  • Reviewing test plans and validation datasets for representativeness, traceability, limitations, production parity, functionality, robustness, calibration, uncertainty, bias, subgroup and equity evidence, and the adequacy of retesting evidence.
  • Reviewing risk and safety controls, guardrails, task boundaries, safe refusal, escalation, fallback, human oversight, training, and other mitigations needed for the intended clinical or operational use.
  • Evaluating human-computer interaction, clinical workflow, usability, automation-bias risk, patient-facing behavior, accessibility, and human-use evidence, and identifying when additional evaluation, clarification, or remediation is required.
  • Assessing whether prior validation remains applicable after changes to the model, data, thresholds, workflow, population, interface, autonomy, guardrails, training, or intended use, and documenting needs for targeted retesting, re-evaluation, or revalidation.
  • Producing clear, traceable review findings and recommended outcomes, including concurrence, concurrence with edits, revision required, additional…
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