Principal Analyst Clinical Risk Management
Listed on 2026-08-06
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Pharmaceutical
Healthcare Compliance, Regulatory Compliance Specialist
Principal Risk Analyst
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Mayo Clinic is seeking an experienced healthcare professional to join the newly established Rochester Clinical Risk Management team as a Principal Risk Analyst. This is a unique opportunity to help build a strategic program advancing patient safety, transparency, organizational learning, and enterprise risk management at one of the world's leading healthcare organizations.
Reporting to the Senior Manager of Clinical Risk Management, the Principal Risk Analyst serves as a senior clinical risk expert who proactively identifies, assesses, and mitigates the clinical, operational, regulatory, financial, legal, and reputational risks associated with patient care. This includes leading the organization's response to complex patient care events, supporting communication and resolution efforts, guiding event review and mitigation activities, and advancing systems, processes, and education that strengthen safety, accountability, and trust.
Key responsibilities include partnering with physicians, administrators, patient safety professionals, legal counsel, accreditation leaders, and operational teams to manage complex matters involving patient care events. The successful candidate demonstrates the ability to assess risk, build trusted relationships, navigate sensitive situations, facilitate difficult conversations, and support leaders and care teams through challenging events — developing practical solutions that balance patient-centered care with organizational priorities while strengthening organizational resilience.
Principal Risk Analyst responsibilities may include receiving direction and reporting to the Director or Senior Manager in the Risk Department. The incumbent will lead risk business operations, special projects, investigations, legal litigation, mitigation development, non-employee access and end user awareness/education. The incumbent will provide guidance to the RD unit for day-to-day operational support, including project management. The incumbent will demonstrate leadership and represent the RD on project teams, committees, strike teams and work groups.
The incumbent will support and develop RD initiatives. Responsible for the design of enterprise business operations, including operational growth and development. Leads multi-disciplinary work groups and projects. Responsible for development of policies and procedures to support the organization's risk tolerance. Gathers and organizes information from a cross-functional investigative team. Works directly with Legal and Human Resources on high risk internal and external investigations.
Works directly with Legal and External Counsel on policy, regulatory and/or litigation matters (using eDiscovery protocols). Completes documentation to support findings including legal reports, SBARs, and executive summaries. Responsible for peer review of work unit documentation. Develops and presents Risk training(s) geared towards Mayo Clinic Leadership. Has extensive experience in regulatory compliance and investigations that includes:
- Deep subject matter expertise in relevant compliance laws and regulations such as privacy compliance, investigations, revenue cycle compliance, device manufacturing compliance, general compliance, conflict of interest;
- Understanding of and ability to apply the Seven Elements of an Effective Compliance Program;
- Ability to carry out audits, assessments and investigations; and
- Ability to use relevant compliance tools including GRC software, monitoring tools, and issue management software.
Ability to follow and apply holds and execute proper preservation of evidence and chain of custody protocols. Depending on role this may include the…
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