Finance and Accounting Manager

Axle Informatics is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision‑making and accelerate research discoveries. We work with premier research organizations and facilities including multiple institutes at the National Institutes of Health (NIH) and other public and private organizations.

• Educational Benefits for Career Growth
• Paid Time Off (Including Holidays)
• Employee Referral Bonus
• 401K Matching
• Flexible Spending Accounts
  • Healthcare (FSA)
  • Parking Reimbursement Account (PRK)
  • Dependent Care Assistant Program (DCAP)
  • Transportation Reimbursement Account (TRN)

Axlerator is seeking an experienced Finance & Accounting Manager to build, lead, and scale a best‑in‑class finance and accounting function and support portfolio management initiatives. This role owns Axlerator’s core accounting operations and financial reporting, while also overseeing financial forecasting, valuation, and performance analysis across our portfolio companies. You will be responsible for establishing and maintaining scalable accounting processes, consolidating and analyzing financial results, designing KPI frameworks and dashboards, supporting valuation efforts, and delivering clear, actionable insights to Axle’s leadership team.

This is a unique opportunity to build and shape a finance and accounting structure with a new mission and perspective, and one that is actively investing in and operating multiple businesses. The Finance & Accounting Manager will play a critical role in driving company growth and long‑term value creation, operating an investor/operator mindset displayed through managing accounting activities but building a scalable, performance‑driven finance organization.

This role requires the ability to work out of our Rockville, MD or Tysons, VA office five days per week.

• Own day‑to‑day accounting operations, including AP, AR, payroll, general ledger, and financial reporting
• Lead monthly, quarterly, and annual close processes with speed, accuracy, and consistency
• Ensure compliance with GAAP, SOX‑aligned controls, and applicable tax and regulatory requirements
• Establish, document, and maintain strong internal controls to mitigate financial and operational risk

• Design and implement institutional‑grade accounting processes, controls, and documentation to support growth, oversight, and complex financial activity
• Build standardized reporting frameworks to support performance monitoring and executive decision‑making
• Track and report key financial and operational KPIs, including close cycle time, reporting timeliness, billing accuracy, cash flow, and error rates
• Drive process standardization, automation, and continuous improvement across finance operations
• Manage internal and external audits and ensure continuous audit readiness

• Oversee fund and investment‑related accounting activities, including tracking capital activity, distributions, and investor reporting
• Monitor the financial health, cash flow, and operating performance of acquired or invested entities
• Support valuation and performance reporting, including fair value analysis and ongoing investment performance tracking
• Provide transactional support for acquisitions and exits, including financial due diligence, integration, and separation activities
• Partner on restructuring, efficiency initiatives, and value‑creation efforts that extend beyond traditional accounting

• Build, manage, and mentor a high‑performing finance and accounting team
• Set clear goals, KPIs, and accountability across the team
• Conduct regular one‑on‑ones, performance reviews, and coaching
• Foster a culture of ownership, accuracy, and continuous improvement

• Oversee financial systems and…