Biologist with Security Clearance

Job Family :
Research Scientists (SCI) Travel Required :
None Clearance Required :
Ability to Obtain Public Trust

What You Will Do:

We are looking for a Biologist to support drug repurposing screening projects, disease model development, assay development, and scientific research activities for the National Center for Advancing Translational Sciences (NCATS). This is a full-time position located in Rockville, MD.
* Work with assay providers for assay development and assay transfer to the TDB program.

* Perform assay development, optimization, and miniaturization activities.

* Conduct high throughput screening using known drugs and bioactive compounds to identify active compounds.

* Confirm primary hits and perform secondary and tertiary assays to narrow candidates to top lead compounds.

* Perform mechanistic studies to characterize lead compounds when necessary.

* Evaluate and apply new technologies and instruments to establish physiologically relevant disease models.

* Characterize human induced pluripotent stem cells (iPSCs) and iPSC-derived cells, including developmental marker analysis and disease phenotype studies.

* Establish human iPSC-derived cell-based assays for disease modeling.

* Lead assay development and compound screening using high-content imaging and flow cytometry assays.

* Operate and maintain high throughput flow cytometry instrumentation, including the iQue flow cytometer.

* Maintain accurate scientific records and communicate effectively with collaborators and project teams.

* Present research findings at internal and external scientific meetings.

* Write, submit, and support the publication of scientific manuscripts.

* Assist team members with manuscript preparation and revisions.

* Collaborate with staff scientists, postdoctoral fellows, IRTA fellows, and external collaborators.

* Mentor and train postbaccalaureate IRTA fellows and summer students.

* Support the overall operational and scientific objectives of NCATS research programs.

* Incumbent capture, no other candidates were considered due to incumbent candidate identified. They meet the labor category requirements provided by the customer

What You Will Need:

* Ph.D. in Molecular, Cell Biology, or Biological Sciences.

* Minimum of EIGHT (8) years of experience in flow cytometry assays.

* Experience in assay development, high-content imaging assay analysis, compound screening, and lead identification.

* Experience with in vitro and in vivo disease model systems.

* Proficiency with Flow Jo, Graph Pad Prism, and Microsoft Office.

* Strong oral and written communication skills.

* Demonstrated ability to write scientific manuscripts and present scientific data and research findings.

* Ability to maintain accurate laboratory documentation and records.

* Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred. What Would Be Nice To Have:
* Background supporting drug repurposing programs.

* Ability to work independently and collaboratively in a multidisciplinary research environment.

* Hands-on use of high throughput screening platforms and technologies.

* Ability to establish disease models using human primary cells or iPSC-derived cells.

* Skilled in mentoring junior researchers, fellows, and students.

* Collaborative approach with external scientific partners and multidisciplinary project teams.

* Scientific publication record in peer-reviewed journals.

* Track record presenting research at national or international scientific conferences. The annual salary range for this position is $-$. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.

What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace. Benefits include:
* Medical, Rx, Dental & Vision Insurance

* Personal and…