Temporary Bone And Matrix Scientist

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Axle is seeking a Temporary Bone and Matrix Scientist to join our vibrant team at the National Institutes of Health (NIH) supporting the National Institute of Child Health and Human Development (NICHD) located in Bethesda, MD.

We are seeking a highly qualified Bone and Matrix Scientist to support laboratory research activities within the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

This position will support the planning, design, and execution of research experiments within the laboratory’s broader research program. The Bone and Matrix Scientist will conduct independent research with an emphasis on bone tissue and bone cell development, evaluate new laboratory techniques and technologies, analyze experimental data, and contribute to scientific reports, presentations, and manuscripts.

• Plan, design, and conduct complex research experiments requiring broad knowledge of scientific theories, principles, and laboratory methods.
• Perform research involving bone tissue, bone cell development, physiology, cell biology, and molecular biology.
• Independently direct and conduct high-priority research projects, including projects focused on developing novel research treatments.
• Advance laboratory research through the development of new procedures, methodologies, and scientific discoveries.
• Evaluate new laboratory techniques, instruments, and software for potential incorporation into existing standard operating procedures.
• Collaborate with investigators and laboratory staff to interpret experiments and evaluate research findings.
• Review scientific data and determine whether new research programs or projects can be developed from an idea or existing data package.
• Design, develop, optimize, and validate experimental assays using a range of laboratory techniques.
• Confirm assay results and develop appropriate secondary assays.
• Research scientific literature and recommend alternative or complementary experimental approaches.
• Troubleshoot difficult screening targets and propose, design, and test alternative assays.
• Perform molecular and cellular biology techniques, including PCR, qPCR, RT-PCR, RT-qPCR, molecular cloning, gel electrophoresis, and nucleic acid extraction and purification.
• Perform protein analysis techniques, including SDS-PAGE, Western blotting, Southern blotting, and ELISA.
• Conduct mammalian cell culture, primary cell culture, bacterial culture, transfections, and related laboratory procedures.
• Perform mouse handling, tissue dissection, tissue sectioning, animal imaging, and genotyping.
• Prepare and submit laboratory animal study protocols for review and approval.
• Provide basic and advanced training to staff on animal care and use procedures.
• Train laboratory personnel in the proper use of laboratory instruments and equipment.
• Advise and assist laboratory users with experimental design, instrumentation, data acquisition, data analysis, and preparation of publication-quality figures.
• Conduct bioinformatics and statistical analyses to support research projects.
• Oversee research data quality and analyze and interpret experimental results.
• Assem…