Senior Scientist - Pharmaceutical Formulation & Process Development

Yoh Life Sciences is hiring a Senior Scientist
- Pharmaceutical Formulation & Process Development for a direct-hire opportunity with a pharmaceutical manufacturing organization in Rosenberg, TX (Greater Houston).

This is a senior-level, hands‑on individual contributor position focused on pharmaceutical formulation and process development, experimental execution, scale‑up, troubleshooting, and technology transfer. The ideal candidate will bring significant pharmaceutical‑industry experience and the ability to personally translate product‑development objectives into scientifically sound experiments, robust manufacturing processes, and successful scale‑up and technology‑transfer activities.

• Title: Senior Scientist
  - Pharmaceutical Formulation & Process Development
• Employment Type: Direct Hire
• Salary: $105,000-$120,000/year
• Location: Rosenberg, TX
  - Greater Houston
• Schedule: Monday-Friday, approximately 8:00 a.m.
  
  -5:00 p.m.
• Work Arrangement: Fully onsite

Limited relocation assistance may be available in the form of a sign‑on bonus for qualified candidates.

Working under the direction of the Director of Research and Development, the Senior Scientist will personally design and execute formulation and process‑development studies from laboratory scale through pilot, engineering, technology‑transfer, and manufacturing activities. The position requires a strong and consistent presence in the laboratory and pilot‑plant environment. This is not a people‑management or primarily administrative role. The Senior Scientist is expected to remain technically hands‑on while serving as a senior scientific resource to other members of the R&D organization.

• Design and personally execute pharmaceutical formulation and process‑development experiments.
• Develop and optimize finished drug‑product formulations and manufacturing processes.
• Evaluate API and excipient properties, compatibility, formulation robustness, and product performance.
• Design scientifically sound experimental plans based on product objectives and development risks.
• Generate, analyze, and interpret experimental data and recommend scientifically justified next steps.
• Apply Quality by Design (QbD) and Design of Experiments (DOE) principles to formulation and process development.
• Identify and evaluate Critical Quality Attributes (CQAs), Critical Material Attributes (CMAs), and Critical Process Parameters (CPPs).
• Perform process optimization, characterization, scale‑up, and technology‑transfer activities.
• Translate laboratory processes into robust pilot‑scale and commercial manufacturing processes.
• Evaluate manufacturing variables including mixing, shear, homogenization, temperature, order of addition, processing time, hold time, transfer, and filling parameters.
• Troubleshoot formulation, process, scale‑up, and manufacturing issues through experimentation and root‑cause analysis.
• Provide hands‑on technical support during pilot, engineering, scale‑up, registration, validation, technology‑transfer, and manufacturing activities.
• Support investigations involving process deviations, product‑performance issues, and manufacturing challenges.
• Collaborate cross‑functionally with Manufacturing, Engineering, Analytical Development, Quality, Regulatory Affairs, and Project Management.
• Prepare and maintain laboratory notebooks, protocols, batch documentation, experimental records, technical reports, and development summaries.
• Operate appropriate laboratory and pilot‑scale pharmaceutical processing equipment.
• Support technical‑transfer documentation and manufacturing implementation.
• Serve as a senior technical resource and mentor scientists and laboratory technicians without formal personnel‑management responsibility.
• Manage multiple technical assignments while maintaining ownership of quality, documentation, and timelines.
• Perform other duties as assigned.

• PhD required in Pharmaceutical Sciences, Pharmaceutics, Pharmaceutical Engineering, Chemical Engineering, or a closely related scientific or engineering discipline.
• Minimum of seven years of relevant pharmaceutical‑industry development experience required.
• Demonstrated hands‑on experience in pharmaceuti…