Principal Manufacturing Associate

Join Immatics and shape the future of cancer immunotherapy; one patient at a time! Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting‑edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T‑cell therapies and TCR bispecifics.

Schedule:

7:00am – 3:30pm;
Monday to Friday (On‑site).

Reports to:

Manufacturing Manager.

Location:

13203 Murphy Road Suite 100, Stafford, TX 77477.

• Biomanufacturing Technology Associate of Applied Science Degree, Biomanufacturing Technology Level 2 Certificate, or equivalent.
• Associate degree in Biology, Biochemistry, Biotechnology, Biomanufacturing, or another related field.
• 7+ years of cell therapy manufacturing experience, or 4+ years of cell therapy manufacturing experience combined with lead or supervisory experience.
• Ability to work productively and participate in a highly creative and fast‑paced environment.

• Provide knowledge and adherence to cGMP requirements.
• Provide leadership, guidance, and necessary training to staff in alignment with cGMP requirements and established procedures.
• Guide staff to facilitate workflow, shift activities, and shift exchange; ensure all activities are completed as assigned.
• Maintain a safe and controlled work environment.
• Support deviation workflow: initiate, investigate, and troubleshoot deviations and unexpected events.
• Serve as backup for manufacturing associates for daily manufacturing processes.
• Review executed batch records and documents.
• Co‑ordinate with the Training Department to include training needs on the manufacturing schedule.
• Ensure clear communication with outgoing and incoming shift leads and managers to disseminate all relevant information.
• Collaborate with the MSAT/PD teams to transfer new projects into GMP.
• Develop or update internal policies, procedures, or steps; identify and elevate risks; communicate changes and plan for execution.
• Lead routine team meetings and huddles.

Work in a cGMP clean‑room environment (Grade A/B/C/D) for approximately 80% of the work hours. Exposure to blood components, temperatures ranging from –196°C to 40°C, liquid nitrogen, dry ice, and carbon dioxide. Lifting duties involve objects up to 25 lbs. and potentially pushing or pulling carts and gas tanks of up to 50 lbs. Candidates must pass a color‑blindness evaluation and assessment of vision abilities required for this position.

• Competitive rates for Health, Dental, and Vision Insurance.
• 4 weeks of vacation granted upfront each year (prorated for first and last years of employment).
• 12 company‑paid holidays.
• 7 days of sick time.
• 100% employer‑paid life insurance up to 1x annual salary, up to $100,000.
• 100% employer‑paid short‑ and long‑term disability coverage.
• 401(k) with immediate eligibility and mandatory company match: 100% up to 3% of base salary the first two years, 4% for years 2‑3, up to 5% from the fourth year onward.
• Parental leave partially paid for eligible employees.
• Optional voluntary benefits: accident, hospital indemnity, critical illness insurance, identity theft protection, pet insurance.

We are an equal‑opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.

We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact

Applicants must be authorized to work in the United States without the need for current or future sponsorship. Visa sponsor ships may be available for certain roles.

Employment is contingent upon successful completion of a background check, reference checks, and pre‑employment drug screening, where permitted by applicable law. For certain roles, additional screenings such as a credit check or motor‑vehicle record review may be required, where job‑related and consistent with business necessity.