Operations Supervisor, Logistics & Cold Chain

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a commercial-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks.

With our purified, high-precision cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.

We have built a state-of-the-art, 100,000-square-foot manufacturing facility in Sacramento, CA (7910 Metro Air Pkwy) to ensure the consistent and reliable delivery of our high-precision cell therapy products. This site is essential to advancing our clinical pipeline and supporting future commercial availability of our life-saving therapies.

leads the teams responsible for the secure, compliant, and on-time movement of donor cells and cell therapy drug products between Orca Bio's Sacramento manufacturing sites and transplant centers nationwide. This is a hands-on people-leadership role that owns end-to-end operational readiness across two functions: the Logistics Specialist team, which coordinates live courier runs, disruption response, chain-of-custody, and vein-to-vein (V2V) performance; and the cold chain / packaging operations hourly team, which prepares, charges, and qualifies shippers and executes GMP packing and handover.

This is a hands-on leadership role. Reporting to the Logistics Program Manager, the Operations Supervisor owns full operational accountability for their team — staffing and qualification currency, KPI performance, real-time disruption response, and continuous improvement — and is expected to be present and available for their team through the parts of the day that matter most. Each Operations Supervisor partners closely with their day-side/night-side counterpart to ensure consistent leadership and a clean handoff between teams.

The ideal candidate is a calm, decisive operator who builds strong teams, thrives in a fast-paced regulated environment, and can move fluidly between strategic planning and real-time problem-solving when a shipment is at risk.

• Production Associate Roles:
  Must have visual acuity of 20/20 (corrected or uncorrected) and normal color vision to safely perform critical tasks such as visual inspection of materials, equipment, and labeling, including distinguishing color-coded components in a GMP environment.
• Most roles must be able to meet cleanroom gowning requirements, including wearing full gowning (face coverings, gloves, hoods, goggles) for extended periods, as needed. Use of cosmetics (makeup, painted nails), jewelry, or facial piercings is not permitted in the cleanroom, and any skin conditions that cause shedding must be disclosed.

• Many roles must be able to work at either Orca Bio Sacramento location (3400 Business Dr. or 7910 Metro Air Pkwy) based on operational needs, as well as regularly participate in video-based meetings. Also, may be required to work scheduled overtime, weekends, or holidays based on business needs.

This role is staffed as two positions one day and one night Supervisor.

These are on-site salaried leadership roles. Rather than working a set schedule, each Operations Supervisor is expected to be present for their team when it matters most — during active courier runs, shift handoffs, coverage gaps, onboarding, and non-routine events — and flex their hours to align with their team's rhythm and the demands of the operation. The two Operations Supervisors coordinate to maintain consistent leadership coverage and a clean handoff between the day and night teams.

• Lead, develop, and retain a cross-trained logistics and cold chain team, setting clear expectations, standards, and accountability.
• Be present and…