Scientist Antibody DiscoveryProtein Engineering

Job Description

The Scientist Antibody Discovery/Protein Engineering will support the Eurofins Discovery Biotherapeutics business in contract research services. This role requires experience and proven knowledge in construct design, antibody formatting and data mining methods with related experience in a contract research organization (CRO) or industry laboratory.

Scientist – Antibody Discovery/Protein Engineering responsibilities include, but are not limited to, the following:

• Performs work in a laboratory setting, meeting the physical job requirements of a lab role
• Conducts production assays primarily in Biotherapeutics Discovery, but may support other Services and activities based on business needs
• Contributes to biologics discovery programs
• Develops and performs assays for Biotherapeutics discovery applications
• Writes and maintains SOPs as required
• Develops new methods supporting project teams both internally and externally for large molecule discovery, characterization, and optimization
• Performs Troubleshooting and Maintenance of equipment employed in the screening process (e.g. liquid handlers, stackers, plate washers, readers)
• Prepares and manages inventory of buffers, reagents, semi-finished and finished goods.
• Provides solutions to complex problems, identifies and initiates process improvements
• Maintains high data quality and reproducibility
• Performs data and report QC review within the department, and may support study director activities
• Takes ownership of client projects with minimal supervision
• Supports validation of new methods, and contributes to expansion of service/product line, equipment, and data management systems
• Completes required training and supports 100% of Employee Health and Safety requirements
• Demonstrates proficiency with care and maintenance of lab equipment and department assets
• Conducts responsible use of confidential IT and business systems, as required
• Adheres to department SOPs and documentation requirements, maintains accurate data management and reporting
• Supports unit goals and demonstrates Eurofins’ competencies, as defined in the job plan
• Provides training to colleagues and external end users, when required
• Contributes to scientific community, and site research and development objectives
• Works effectively in a team environment, under minimum direction, to achieve business production, project timelines, and quality objectives
• Adjusts work hours and provides cross-functional support to other departments, as required, and maintains accountability in delivering to client needs/timelines
• Routinely communicates project updates to internal and external clients
• Performs other duties, as assigned

Basic Minimum Education al Requirements

• B.S. with 5 years relevant experience
• M.S. with 3 years relevant experience
• Ph.D. with 0 years post-doctoral experience

Basic Minimum Qualifications

• Direct experience with construct design (antibody and non-antibody proteins), preferably in a contract research organization or industry laboratory, for large molecule discovery applications
• Direct experience with antibody discovery methodology
• Familiarity with concepts of extracting data from the literature and FTO
• Demonstrated proficiency in contributing independently on a project team with time and quality deliverables
• Good communication and interpersonal skills
• Experience working in a Quality Management System
• Scientific expertise with antibody discovery methodology
• Scientific expertise with different types of protein design, optimization and production
• Scientific expertise in protein production, purification and QC of proteins (antibody and non-antibody)
• Scientific expertise with construct design for cell line development
• Familiarity with mining public or non-public resources of antibody analysis (immunogenicity, stability, solubility etc.) for antibody engineering and design
• Background knowledge of sequence-structure-function correlation
• Experience in leading and delivering results in R&D or innovation programs
• Authorization to work in the United States indefinitely without restriction or sponsorship.

The Ideal Candidate Possesses the Following:

• Ability to read, write, and interpret documents, such as…