Biopharma Services

Senior Bioanalytical Chemist - Scientist II

Full-time position at Eurofins Discovery Services North America, LLC located in Saint Charles, MO.

• Performs work in a laboratory setting, meeting the physical job requirements of a lab role.
• Conducts production assays primarily in ADME Toxicology Services, but will also support Bio Therapeutics Services based on business needs.
• Develops Liquid Chromatography‑Mass Spectrometry (LC‑MS) methods for ADME/DMPK applications.
• Develops analytical methods supporting project teams both internally and externally for new assay development.
• Performs troubleshooting and maintenance of Mass Spectrometers and HPLC units. Experience with Sciex® or Thermo High‑Resolution/ Accurate Mass Instrumentation is a plus.
• Prepares and manages inventory of buffers, reagents, semi‑finished and finished goods.
• Provides solutions to more complex problems, identifies and initiates process improvements.
• Maintains high data quality and reproducibility.
• Performs data and report QC review within the department, and may support study director.
• Takes ownership of client projects with minimal supervision.
• Supports validation of new methods, and contributes to expansion of service/product line, equipment, and data management systems.
• Understands and complies with requirements for work performed at a GxP site.
• Completes required training and supports 100% of Employee Health and Safety requirements.
• Demonstrates proficiency with care and maintenance of lab equipment and department assets.
• Conducts responsible use of confidential IT and business systems, as required.
• Adheres to department SOPs and documentation requirements, maintains accurate data management and reporting.
• Supports unit goals and demonstrates Eurofins’ competencies, as defined in the job plan.
• Provides training to colleagues and external end users, when required.
• Contributes to scientific community, and site research and development objectives.
• Works effectively in a team environment, under minimum direction, to achieve business production, project timelines, and quality objectives.
• Adjusts work hours and provides cross‑functional support to other departments, as required, and maintains accountability in delivering to client needs/timelines.
• Routinely communicates project updates to internal and external clients.
• Performs other duties, as assigned.

• Direct/Demonstrated experience with Liquid Chromatography‑Mass Spectrometry (LC‑MS) in a contract research organization or industry laboratory in one or more of the following areas:
• Bioanalytical Method Development for Small and/or Large Molecules
• Drug Metabolism and Metabolite Identification
• Mass Spectrometry Based Proteomics
• Direct/Demonstrated experience with LC‑MS systems and troubleshooting
• Demonstrated proficiency in contributing independently on a project team with time and quality deliverables
• Good communication and interpersonal skills
• Experience working in a Quality Management System
• Ability to work in the U.S.
  indefinitely without sponsorship

• B.S. with 10 years relevant experience
• M.S. with 7 years relevant experience
• Ph.D. with 3 years relevant experience
• Or an equivalent of education and experience

• Demonstrated experience with validation of bioanalytical methods in accordance with regulatory (FDA, ICH, OECD) guidelines
• Experience with liquid handling, automation, solid‑phase extraction (SPE), HTS applications, and large‑scale screening
• Experience with Sciex® or Thermo® High Resolution/ Accurate Mass Instrumentation and Associated Software is a plus.
• Experience in small team leadership and project management
• Experience in leading and delivering results in R&D or innovation programs

• Ability to read, write, and interpret documents, such as standard operating procedures and technical reports
• Ability to perform mathematical calculations, statistical analyses, and data interpretation
• Ability to multitask with organization and manage time effectively
• Ability to solve practical problems and troubleshooting skills
• Ability to work in a laboratory setting, according to…