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Principal Project Engineer

Job in St. Louis, Saint Louis, St. Louis city, Missouri, 63105, USA
Listing for: BEPC Inc. - Business Excellence Professional Consulting
Full Time position
Listed on 2026-07-23
Job specializations:
  • Engineering
    Pharma Engineer, Validation Engineer, Quality Engineering
Salary/Wage Range or Industry Benchmark: 120000 - 190000 USD Yearly USD 120000.00 190000.00 YEAR
Job Description & How to Apply Below
Location: St. Louis

Employment Type: W2 Contract – 12 Months with the Possibility of Extension

Shift: Monday – Friday | Standard Business Hours (40 hours/week)

Work Model: Fully Onsite

Role Overview

BEPC is seeking a Principal Project Engineer to support a major life sciences capital expansion project in Saint Louis, MO. This senior‑level role is responsible for leading engineering work streams on pharmaceutical facility projects, ensuring successful execution from design through construction while maintaining compliance with cGMP and regulatory requirements.

The ideal candidate will have extensive experience managing pharmaceutical capital projects, including cleanroom design, brownfield facility expansions, and construction oversight. This individual will collaborate with cross‑functional teams, drive project decisions, manage technical risks, and ensure projects are completed safely, on schedule, and within budget.

Key Responsibilities
  • Lead engineering work streams for large-scale pharmaceutical capital projects.
  • Provide senior‑level project engineering and technical leadership throughout project execution.
  • Collaborate with site, engineering, project management, and construction teams to drive timely project decisions.
  • Manage project scope, schedules, budgets, risks, and technical deliverables.
  • Review engineering drawings, construction submittals, RFIs, and technical documentation.
  • Support cleanroom design, classified manufacturing spaces, qualification, and validation activities.
  • Ensure compliance with cGMP regulations, industry standards, and pharmaceutical engineering practices.
  • Develop technical specifications based on customer and project requirements.
  • Identify project risks and implement mitigation strategies.
  • Drive change management while maintaining strong stakeholder relationships.
  • Independently manage assigned work streams and maintain accurate project documentation.
  • Support construction activities and resolve technical issues throughout execution.
Required Qualifications
  • Bachelor's degree in Engineering required (Process Engineering preferred).
  • Minimum of 15 years of capital project engineering experience.
  • Extensive experience managing pharmaceutical or life sciences capital projects.
  • Pharmaceutical manufacturing experience is required.
  • Cleanroom and classified manufacturing space experience is required.
  • Brownfield project experience is highly preferred.
  • Strong knowledge of cGMP regulations, pharmaceutical facility standards, and engineering best practices.
  • Ability to interpret engineering drawings, specifications, and construction documents.
  • Experience supporting qualification and validation activities.
  • Strong leadership, communication, negotiation, and stakeholder management skills.
  • Proven ability to manage complex engineering work streams independently.
  • Strong problem‑solving, critical thinking, and decision‑making abilities.
  • Ability to travel to and work onsite in Saint Louis, MO Monday through Friday.
Education
  • Bachelor of Science in Engineering required.
  • Process Engineering background preferred.
Preferred Qualifications
  • Experience with pharmaceutical facility expansions.
  • Experience leading multidisciplinary engineering teams.
  • Experience managing construction activities in active manufacturing facilities.
  • Strong background in project risk management.
  • Experience supporting engineering change management.
  • Familiarity with capital project delivery methodologies for life sciences facilities.
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