Accounting Manager, Financial Operations & Reporting

The Genome Partnership is a not-for-profit organization based in St. Louis that advances research, promotes education, and expands commerce in genome science and technology. Since 1999, it has united many of the world’s leading researchers, innovators, and industry pioneers through the Advances in Genome Biology and Technology (AGBT) meetings.

As we transition key financial functions in-house, we are seeking an experienced Accounting Manager to oversee day-to-day accounting operations and lead core financial processes. This role combines hands-on execution with managerial ownership of financial reporting, internal controls, audit coordination, and budgeting. The Accounting Manager will serve as a trusted partner to executive leadership, helping build scalable systems that support the organization’s mission and growth.

• Own the full-cycle accounting process, including accounts payable, accounts receivable, payroll, and general ledger maintenance
• Manage weekly AP payment runs via  in alignment with cash flow forecasts and leadership priorities
• Maintain vendor records, W-9s, and oversee annual 1099 preparation
• Oversee expense report processing and reimbursements to ensure accuracy and a positive stakeholder experience
• Administer bi-weekly payroll through ADP; reconcile payroll entries to the general ledger and bank activity

• Lead the annual budgeting process and quarterly forecasting to support organizational planning
• Prepare quarterly financial reports, variance analyses, and dashboards for leadership and the Board
• Maintain rolling cash flow forecasts and provide scenario analysis to support decision-making
• Reconcile meeting-related revenues and expenses, including sponsor ships, registrations, and direct event costs, and ensure alignment across budgets, forecasts, and actual results

• Manage monthly, quarterly, and annual close processes, ensuring accurate and timely financial reporting
• Prepare and review journal entries, reconciliations, and supporting schedules
• Develop, document, and maintain accounting policies, procedures, and internal controls
• Maintain process documentation and control narratives to support audit readiness

• Serve as the primary accounting liaison for the annual external audit
• Coordinate preparation of audit schedules, respond to auditor inquiries, and support timely completion
• Support external reporting requirements, including audited financial statements, IRS Form 990, and state filings
• Provide financial reporting and analysis in support of Board and committee oversight

• Monitor cash balances, bank activity, and short-term investments
• Align payment timing with liquidity needs and reserve targets
• Flag variances and recommend actions related to collections, payment timing, or cash positioning

• Support the accounting and payment of employee benefit plans, including reconciliation of benefits invoices, payroll deductions, and employer contributions
• Assist with the accounting, payment, and tracking of business insurance premiums (e.g., health benefits, general liability, D&O, cyber, workers’ compensation)
• Provide financial schedules and documentation related to benefits and insurance for leadership, auditors, and external advisors

• Provide financial tracking and reporting support for the Endowment and Investment Committee

• Provide accounting support to affiliated organizations under contracted-services agreements, as approved
• Ensure strict separation of financial records, systems, and internal controls in accordance with governance and audit standards
• Track time and activity to support accurate cost allocation and transparency

• Perform other accounting-related duties and cross-functional financial support as needed to ensure accurate reporting, compliance, and operational continuity in a small organization

• Bachelor’s degree in…