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Senior IT Infrastructure & Operations Manager

Job in St. Louis, Saint Louis, St. Louis city, Missouri, 63105, USA
Listing for: myDNA, Inc.
Full Time position
Listed on 2026-07-04
Job specializations:
  • IT/Tech
    IT Project Manager, Systems Administrator, IT Infrastructure, Cloud Computing: Infrastructure & Operations
Salary/Wage Range or Industry Benchmark: 100000 - 130000 USD Yearly USD 100000.00 130000.00 YEAR
Job Description & How to Apply Below
Location: St. Louis

Senior IT Infrastructure & Operations Manager

Our Purpose

Our mission is to build a healthier and more connected world with precision health and genealogy services. We empower individuals with actionable insights into their genetic makeup, fostering a deeper understanding of their ancestry, health, and wellness. By integrating the experience of Gene by Gene Laboratory Services, Family

TreeDNA genealogy, and myDNA reporting services, we strive to deliver cutting‑edge genetic testing and personalized solutions that inspire informed decisions and enhance quality of life. Our team is dedicated to advancing the field of genomics through innovation, research, and a commitment to excellence.

Our Values

All employees are expected to demonstrate our values of Innovate
, One Team
, and Integrity when carrying out the accountabilities and responsibilities of their role. This is how we show up every day for ourselves, our colleagues and our customers and strategic partners to deliver our vision and strategic goals.

Position Overview

The Senior IT Infrastructure & Operations Manager will own and scale the internal technology infrastructure, IT services and operations, ensuring that our labs, offices, and remote staff are running reliably and securely across the organization. This is a working manager role. Reporting to the Chief Information Technology Officer, you will own the day‑to‑day operation of our Systems team and forward direction of the IT service desk, systems operations, networking, cloud and data center environments.

This role manages and maintains on‑call rotation for after‑hours coverage across the Infrastructure and Systems team for incident response.

The role will be expected to translate business and technology objectives into resilient infrastructure, strong end‑user support, and a mature security posture, while managing the teams, vendors, and budgets that underpin these services. The Manager will act as a senior escalation point of accountability for uptime, internal end‑user experience, major incidents and security events and will partner closely with internal stakeholders to ensure technology enables, rather than constrains, business performance.

In addition to broad business‑as‑usual responsibilities, this role will also provide opportunities to lead and contribute to interesting projects as required for a growing business. Equally important will be an aptitude for combining technical depth with commercial judgment to deliver dependable and cost‑effective operations, a flair for building highly collaborative working relationships, and the energy and drive to manage competing priorities in a growth‑focused and high‑performing corporate environment.

Accountabilities

and Responsibilities Systems & Infrastructure Operations
  • Define the organization’s requirements, standards, and roadmap for on‑premises and cloud infrastructure, including compute, storage, virtualization, network, and identity.
  • Ensure systems are designed and implemented for availability, performance, scalability, and recoverability in line with business requirements.
  • Direct infrastructure portfolios, including upgrades, migrations, and capacity planning, ensuring delivery on time and within budget.
  • Establish and govern configuration, patching, and lifecycle management standards across the server and platforms.
  • Define, maintain, and oversee the testing of backup, disaster recovery, and business continuity capabilities.
  • Strategically evaluate and recommend new technologies that improve reliability, efficiency, or cost.
Fostering Team Success
  • Model leadership and champion an institutional commitment to safety and risk mitigation in the workplace.
  • Champion and align organizational directives with organizational values, procedures, and systems.
  • Provide strategic leadership, development, and mentorship to the infrastructure, operations, service desk, and security teams.
  • Set strategic objectives, manage performance frameworks, and build the capability and resilience of the team.
  • Act with the mindset of a strategic business partner; collaborate and drive alignment when required to create win‑win outcomes and continuous improvement.
  • Demonstrate…
Position Requirements
10+ Years work experience
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