Manager, Global Supply Planning

Remote/Philadelphia, PA

Cabaletta Bio (Nasdaq: CABA) is a clinical-stage biotechnology company focused on developing and launching the first curative targeted cell therapies designed specifically for patients with autoimmune diseases. The CABA™ platform encompasses two complementary strategies which aim to advance the discovery and development of engineered T cell therapies with the potential to become deep and durable, perhaps curative, treatments for a broad range of autoimmune diseases.

The lead CARTA (Chimeric Antigen Receptor T cells for Autoimmunity) strategy is prioritizing the development of rese-cel, a 4-1BB-containing fully human CD19-CAR T cell investigational therapy. Rese-cel is currently being evaluated in the RESET™ (REstoring SElf-Tolerance) clinical development program spanning multiple therapeutic areas, including rheumatology, neurology and dermatology. Cabaletta Bio’s headquarters and labs are located in Philadelphia, PA. For more information, please visit  and connect with us on Linked In.

Uniquely Differentiated. Rapid. Elegant.

At Cabaletta, we are driven by the shared mission of developing cures, where a patients’ own cells are used to fight disease. We are building a culture grounded in the knowledge that successful cures can be achieved for patients if every member of the Cabaletta is focused on the success of the team. To nurture this, we make an active commitment to the well‑being and continuous growth of each employee who joins the team.

In this way, we are not only working to improve the lives of patients, but of everyone involved. #Cabaletta Crew.

We’re proud to be a Great Place to Work-Certified™ company! #GPTWcertified Check out what our employees say makes working here so great:
Working at Cabaletta Bio Inc | Great Place to Work®

Reporting to the Director, Network Planning, the Manager, Global Supply Planning is responsible for supporting and managing the end‑to‑end (E2E) supply planning activities for Cabaletta Bio's cell and gene therapy supply chain. This includes supporting clinical and commercial manufacturing at Contract Development and Manufacturing Organizations (CDMO's), internal production of material supporting product release, and biorepository forecasting.

• Complete the monthly supply planning cycle, including crafting and updating 36‑month supply plans and identifying key supply decisions.
• Conduct replenishment planning at external partners in support of all manufacturing requirements in coordination with Inventory Management, Logistics, and Supplier Management.
• Prepare supply planning input for the monthly S&OP cycle and annual budget cycle.
• Maintain all supply‑related parameters and master data in relevant planning systems, managing product lifecycle changes.
• Participate in design and implementation of new ERP system.
• Assist in translating KPI Supply Chain metrics into actionable tasks in collaboration with CMC and VST
• Identify and implement key supply chain related initiatives with internal stakeholders and external partners to improve supply chain efficiency.

• Bachelor’s degree or equivalent (Preferred concentration in Engineering, Supply Chain or Business Management/Sciences)
• 5-7 years of supply chain experience with a strong focus on supply planning. Relevant supply chain planning experience in autologous cell & gene therapy is ideal.
• APICS or similar certification preferred.
• 2+ years’ experience with ERP system, preferably Net Suite
• Working knowledge of regulatory frameworks (FDA, EMA etc), GMP manufacturing and GMP storage requirements.

Our name – Cabaletta – is derived from the operatic term that represents a rapid, repetitive, and technically challenging section of an operatic aria, designed to showcase the skills of the lead singer. Analogously, Cabaletta Bio strives to achieve rapid and repetitive product development, building on our indication prioritization and biologic platform that targets the driver of specific autoimmune diseases without the need for long‑term immunosuppression.

For more information, please visit

• Our most important asset is our people, and we offer competitive benefits, PTO, and stock option plans.

Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.