Post Doctoral Fellow

Postdoctoral Research Fellow

Founded in 1818, Saint Louis University is one of the nation's oldest and most prestigious Catholic universities. SLU, which also has a campus in Madrid, Spain, is recognized for world-class academics, life-changing research, compassionate health care, and a strong commitment to faith and service.

Saint Louis University's Department of Neurology invites applications for a Postdoctoral Research Fellow to join our multidisciplinary team working on an NIH-funded project. The project investigates alcohol-induced cerebrovascular dysfunction, focusing on the role of lipid signaling in blood-brain barrier (BBB) disruption and neuroinflammation. The postdoctoral fellow will be involved in MCAO surgeries, biochemical analysis, and behavioral testing in a cutting-edge research environment.

This position offers an opportunity to conduct innovative research on the effects of alcohol exposure on cerebrovascular health and neuroinflammation.

Responsibilities:

• Perform Middle Cerebral Artery Occlusion (MCAO) surgeries to model ischemic stroke in mice.
• Conduct biochemical assays to analyze lipid signaling, enzyme expression, and oxidative stress markers in brain tissue.
• Perform Western blotting, PCR, immunohistochemistry, and fluorescence imaging.
• Coordinate and execute behavioral studies to assess cognitive and motor deficits, including Morris Water Maze (MWM), Novel Object Recognition (NOR), and Fear Conditioning Tests (FCT).
• Collaborate with laboratory team members on experimental design, data analysis, and manuscript preparation.
• Contribute to grant writing and publication of research findings in peer-reviewed journals.

Minimum Qualifications:

• A PhD in Neuroscience, Neurobiology, or a related field.
• Experience in surgical techniques, specifically MCAO, for stroke models in mice.
• Strong background in biochemical assays, including Western blotting, PCR, and immunohistochemistry.
• Experience with behavioral analysis in mice.
• First-author publication history in peer-reviewed journals.
• Strong communication skills and ability to collaborate with a diverse team of researchers.

Preferred Qualifications:

• Experience with lipid signaling, autotaxin, and LPP3 pathways in cerebrovascular research.
• Knowledge of animal models of neuroinflammation and ischemic stroke.
• Familiarity with neuroimaging techniques and data analysis tools (e.g., ImageJ, Graph Pad Prism).

Position Details:

• Location:
  
  Saint Louis University School of Medicine, Department of Neurology, St. Louis, MO.
• Full-time, 40 hours/week.
• Compensation:
  Competitive salary with benefits.

How to Apply:

Interested candidates should submit the following materials to Dr. Manikandan Panchatcharam:

• Cover letter addressing qualifications and interest in the position.
• Curriculum Vitae (CV) with a list of publications.
• Contact information for three references.

Saint Louis University is an Equal Opportunity/Affirmative Action Employer. We encourage applications from individuals with disabilities, minorities, women, and veterans.