Staff Scientist - Neurosurgery

Position Summary

Scheduled

Hours:

40 hours per week. The Staff Scientist will provide advanced technical support for translational immunology and neuro‑oncology research focused on T‑cell trafficking, tumor immunology, and CAR‑T cell therapy for brain tumors. The researcher will perform and optimize complex laboratory procedures including tissue and blood processing, multiparameter flow cytometry, immunofluorescence and immunohistochemical staining, cell culture, CAR‑T cell functional assays, cytokine analyses, molecular biology techniques, and animal tumor studies.

Responsibilities include data collection, quality control, laboratory record‑keeping, and analysis of experimental results.

• Design research protocols following instructions from the principal investigator and develop procedures for collection, verification, and management of data.
• Process brain tumor and peripheral blood specimens.
• Perform flow cytometry, T‑cell phenotyping, and functional immune assays.
• Conduct immunofluorescence, immunohistochemistry, and image analysis.
• Generate and evaluate CAR‑T cells using in vitro cytotoxicity assays.
• Perform cytokine profiling, ELISA‑based assays, and molecular biology workflows.
• Support murine brain tumor studies, including treatment administration and tissue collection.
• Maintain experimental datasets, perform basic statistical analyses, and ensure rigorous documentation and quality control.
• Document research topics and prepare and submit manuscripts for publication or presentation at scientific meetings.

• Master’s degree OR equivalent education and/or experience (minimum education).
• 3+ years of laboratory operations experience.

• Ph.D. in a related field.
• Analytical problem‑solving, communication, computer literacy, data analysis, and data interpretation skills.

Grade R10 – $48,000.00 – $86,900.00 per annum (base salary; determined by qualifications, performance, and market rates).

• Up to 22 days of vacation, 10 recognized holidays, and sick time.
• Competitive health insurance packages with priority appointments and lower copays/coinsurance.
• Free Metro transit U‑Pass for eligible employees.
• Defined contribution (403(b)) retirement savings plan with university matching starting at 7%.
• Wellness programs: challenges, annual health screenings, mental health resources, mindfulness courses, employee assistance program, financial resources, and dietitian access.
• 4 weeks of caregiver leave to bond with a new child; additional family care resources available.
• Tuition coverage for the employee and dependents (up to 100% for WashU, 40% elsewhere after seven years).

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.