Senior Research Technician - Neurosurgery

Scheduled

Hours:

40

The Senior Research Technician will provide technical support for translational immunology and neuro‑oncology research focused on T‑cell trafficking, tumor immunology, and CAR‑T cell therapy for brain tumors. The researcher will perform and optimize complex laboratory procedures including tissue and blood processing, multiparameter flow cytometry, immunofluorescence, immunohistochemical staining, cell culture, CAR‑T cell functional assays, cytokine analyses, molecular biology techniques, and animal tumor studies.

The technician will independently design and conduct complex research studies, experiments, and assays.

• Perform complex analysis/projects according to research protocols and explain methods and procedures to other technicians.
• Process brain tumor and peripheral blood specimens.
• Perform flow cytometry, T‑cell phenotyping, and functional immune assays.
• Conduct immunofluorescence, immunohistochemistry, and image analysis.
• Generate and evaluate CAR‑T cells using in vitro cytotoxicity assays.
• Perform cytokine profiling, ELISA‑based assays, and molecular biology workflows.
• Support murine brain tumor studies, including treatment administration and tissue collection.
• Maintain experimental datasets, perform basic statistical analyses, and ensure rigorous documentation.
• Assure compliance with established safety procedures and maintain required laboratory documentation.
• Ensure laboratory and equipment cleanliness and maintenance following established procedures.

Lab environment with potential exposure to biological and chemical hazards. Must be physically able to wear protective equipment and provide standard care to research animals.

• Education:
  
  Master’s degree or combination of education and/or experience may substitute for minimum education.
• Certifications/Professional Licenses:
  None required.
• Work Experience:
  
  Laboratory setting (1 year).
• Skills:
  
  Not applicable.

• Education:
  
  No additional education unless stated elsewhere.
• Certifications/Professional Licenses:
  None unless stated elsewhere.
• Work Experience:
  
  None unless stated elsewhere.
• Skills:
  
  Communication, Laboratory Instrumentation, Recordkeeping, Software Program, Working Independently.

Grade R08‑H. Salary Range: $18.77 – $31.94 per hour. Individual rates within this range are determined by qualifications, performance, equity, market rates, and department budget.

• Up to 22 days of vacation, 10 recognized holidays, and sick time.
• Competitive health insurance packages with priority appointments and lower copay/coinsurance.
• Free Metro transit U‑Pass for eligible employees.
• Defined contribution (403(b)) retirement savings plan; employee contributions matched up to 7% by the university.
• Wellness programs: challenges, health screenings, mental health resources, mindfulness courses, employee assistance program, financial resources, and access to dietitians.
• Family leave: 4 weeks of caregiver leave, tuition coverage for dependent undergraduate students.

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the university’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status or genetic information.