Staff Scientist - Developmental Biology

Position Summary

The Mokalled Laboratory investigates the cellular and molecular mechanisms that enable successful spinal cord regeneration and applies these discoveries to mammalian models of nervous system repair. Our research integrates zebrafish genetics, human iPSC‑derived neuronal models, single‑cell genomics, advanced imaging, and functional assays to identify repair‑associated cell states and therapeutic targets that promote neuronal survival, axon regeneration, and recovery after spinal cord injury.

The Staff Scientist will establish and optimize human iPSC‑derived neuronal models, develop assays to investigate vesicular trafficking and activity‑dependent neuronal repair, integrate mammalian systems with discoveries from zebrafish regeneration, and provide technical leadership and mentoring in advanced neuronal culture and imaging methodologies. Designs research protocols and assists in developing and conducting research projects, including experiment design, data analysis, and documentation of experiment results.

• Following instructions and discussions with the principal investigator, designs research protocols, including developing procedures for the collection, verification and management of data.
• Assists with grant preparation and reporting.
• Performs complex statistical analysis of data collected and writes interpretative reports.
• Verifies the correctness of the data submitted and makes recommendations based on these analyses.
• Documents research topics and prepares and submits papers based on research work to publications and committees for publication or presentation to peers.
• Solves practical problems relating to difficulties with equipment or test subjects.
• Suggests technical or procedural improvements in testing methods.
• Conducts literature searches related to research project.
• Performs other duties as assigned.

Works in a laboratory environment with potential exposure to biological and chemical hazards. Must be physically able to wear protective equipment and to provide standard care to research animals.

• Education:
  
  Master’s degree or combination of education and/or experience may substitute for minimum education.
• Certifications/Professional Licenses:
  None required.
• Work Experience:
  
  Laboratory Operations (3 years).
• Skills:
  
  Not applicable.

• Ph.D. in Neuroscience, Cell Biology, Developmental Biology, or a related field.
• Experience with human iPSC‑derived neuronal differentiation and culture.
• Expertise in mammalian neuronal biology, synaptic or vesicular trafficking, and advanced fluorescence microscopy.
• Experience with CRISPR, quantitative image analysis, and molecular biology techniques.
• Strong record of independent research and scientific communication.

Grade R10 Salary Range $48,000.00 - $86,900.00 / Annually.

Up to 22 days of vacation, 10 recognized holidays, and sick time. Competitive health insurance packages with priority appointments and lower copays/coinsurance. Free Metro transit U‑Pass for eligible employees. 403(b) retirement savings plan with contributions starting at 7%. Wellness challenges, annual health screenings, mental health resources, mindfulness programs, and employee assistance program.

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and provides equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.