Research Specialist - Pediatrics Newborn Medicine

Position Summary

The newly forming Alfano lab focuses on the mechanisms of pathogen-specific molecular determinants of sepsis and endothelial dysfunction. The goal of our research is to determine the factors that confer increased risk of life-threatening sepsis to certain populations and provide novel insights into future therapeutic developments. We utilize extensive in vivo and in vitro modeling of bacterial infection in concert with both bacterial and host genetic perturbation to examine the host-bacterial interaction.

Experimental approaches involve endothelial cell culture, bacterial culturing, microscopy, flow cytometry, molecular biology, functional cell-based in vitro assays, and in vivo murine infection models. Our work operates alongside the mentorship of the Bubeck Wardenburg lab at WashU Medicine. Provides critically complex research and experimentation for department/s allowing the advancement of scientific analysis and discovery. Serves as a subject matter expert offering support, training and guidance relative to the discipline/area.

May participate and or present on the research developed, or the established work of those within the department.

SAINT LOUIS, MO 63110

40

• Performs complex analyses, experiments and project work under general direction of the PI. Serves as representative for PI and ensures procedures and protocols are adhered to consistently and effectively meet department's standard. Exhibits a high degree of independent problem solving and ability to conduct research on assigned projects. May serve in lead role as needed.
• Plans, develops, organizes and formalizes research results and findings. May develop for presentation and/or present on behalf of department. Conducts literature searches related to research projects. Writes/co-authors publications and/or papers supporting research findings in logical and sometimes multiple formats tailored to audiences. May participate in work related to grants.
• Solves practical problems relating to difficulty with equipment or test subjects. Suggests technical/ procedural improvements in various methods. May develop and optimize experimental procedures and protocols. Provides high-level troubleshooting to advance process or lab procedures.
• Serves as department's research representative and may participate in various related meetings and events. Gathers/delivers data/information and serves as subject matter expert. Performs statistical data analysis, as needed. Presents research information to internal and/or external audiences.
• Organizes and maintains required documentation on lab and/or specimen conditions and can develop and summarize information into usable formats or presentations on behalf of the department. May communicate findings to various users or external audiences.
• Performs all related work in accordance with established protocols and safety/compliance requirements.
• May explain methods, lead or train other personnel or observers.

• Works in a laboratory environment with potential exposure to biological and chemical hazards as well as BSL2 pathogens.
• Must be physically able to wear protective equipment and to provide standard care to research animals.

Master’s degree or combination of education and/or experience may substitute for minimum education.

No specific certification/professional license is required for this position.

Laboratory Setting (4 Years)

Not Applicable

A driver's license is not required for this position.

WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles.

No additional education unless stated elsewhere in the job posting.

No additional certification/professional licenses unless stated elsewhere in the job posting.

No additional work experience unless stated elsewhere in the job posting.

Critical Thinking, Detail-Oriented, Laboratory Instrumentation, Laboratory Research, Oral Communications, Recordkeeping, Self-Starter, Software Program, Spreadsheets, Statistical Software, Written Communication

R09

$41,700.00 - $75,600.00 / Annually

The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.

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