Research Technician II - Pathology & Immunology

Location: St. Louis

Location SAINT LOUIS, MO 63110

Scheduled Hours
40

Position Summary Our research group is focused on understanding surveillance processes of the immune system, and the sabotage mechanisms used by pathogens to evade detection and host-mediated elimination. We use the techniques of protein biochemistry, x-ray crystallography and computational biology to determine the three-dimensional structures of proteins and investigate their macromolecular interactions. Current interests of the lab include proteins associated with classical MHC antigen processing and presentation pathways, non-classical MHC family members and natural killer cell activating and inhibitory receptors.

We are also actively studying a number of virally encoded proteins that enable host immune evasion. Large-DNA viruses (i.e., herpes viruses and pox viruses) have evolved a myriad of strategies that include the sabotage of antigen processing, the molecular mimicry of host signaling molecules and the sequestration of cytokines and chemokines by novel decoy receptors. Our approach to investigate these systems is based on the production of large quantities of soluble protein in heterologous expression systems, allowing for cognate ligand/ receptor discovery, biophysical interaction analyses, high-resolution structure determinations and targeted functional studies.

Together, these approaches provide a wealth of information on the basic tools with which the immune system operates.

Assists with the technical aspects of studies and experiments, including documentation and preparation of materials.

Job Description Primary

Duties & Responsibilities:

Assists with research studies, experiments and assays, including collection of data, preparation of solutions and setup and maintenance of equipment.

Performs data entry and maintains data files on research.

Prepares tissue cultures, reagents, probe tests, etc.

Complies with established safety procedures and maintains required documentation on laboratory and specimen conditions.

Ensures lab conditions and equipment are properly cleaned and maintained in accordance with established procedures.

Assists with general lab maintenance and cleaning.

Performs other duties as assigned.

Working Conditions:

This position works in a laboratory environment with potential exposure to biological and chemical hazards.

The individual must be physically able to wear protective equipment and to provide standard care to research animals.

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Required Qualifications

Education:

Bachelor’s degree or combination of education and/or experience may substitute for minimum education.

Certifications /Professional Licenses :

No specific certification/professional license is required for this position.

Work Experience:

No specific work experience is required for this position.

Skills:

Not Applicable Driver's License:

A driver's license is not required for this position.

More About This Job The ideal candidate will have up to one year of experience in a laboratory setting.

Preferred Qualifications

Education:

No additional education unless stated elsewhere in the job posting.

Certifications /Professional Licenses :

No additional certification/professional licenses unless stated elsewhere in the job posting.

Work Experience:

No additional work experience unless stated elsewhere in the job posting.

Skills:

Communication, Detailed Reports, Laboratory Instrumentation, Laboratory Research, Protein Biochemistry, Software Program, Working IndependentlyGradeR
06-HSalary Range $16.92 - $26.44 / Hourly The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.

Questions For frequently asked…