Principal Engineer

Principal Engineer (St. Louis, MO)

Principal Engineer to lead IT project strategies in software architecture & development of digital, data, and AI solutions, leveraging cloud-native, event-driven, and serverless architectures; lead teams in implementing & operating secure, scalable, and resilient architectures for automation, observability, and self-service platforms; design & implement real-time data, analytics, and AI solutions; mentor & train engineers.

• Lead IT project strategies in software architecture & development of digital, data, and AI solutions, leveraging cloud-native, event-driven, and serverless architectures.
• Lead teams in implementing & operating secure, scalable, and resilient architectures for automation, observability, and self-service platforms.
• Design & implement real-time data, analytics, and AI solutions.
• Mentor & train engineers.

• Master’s degree in Computer Science, Software Engineering, Electrical Engineering, or closely related field.
• Minimum 3 years of experience in a consumer health, life sciences and/or pharmaceutical environment.
• Experience designing & operating GxP Lake houses in compliance with 21 CFR Part 11 and Eudra Lex Annex
  11 using AWS Sagemaker Unified Studio, Databricks, and Microsoft Fabric.
• Implementing Zero‑Trust and Governance‑as‑Code to automate security controls.
• Using Terraform to automate Installation Qualification and Operational Qualification documentation within CI/CD and/or Dev Sec Ops  pipelines and regulatory workloads.
• Designing & implementing real-time Agentic AI strategies and life sciences business flows for autonomous reasoning and RAG implementations.
• Scaling AI‑MLOps using Sage Maker, EKS, and/or Databricks, including Federated Learning & Explainable AI for clinical validation.
• Applying Differential Privacy, Safety & Federated Learning to patient datasets for cross-border AI training.
• Managing engineering delivery & excellence within Global Capability Centers.

Telecommuting permissible from home office location within reasonable commuting distance of St. Louis, MO up to 2 days per week. Up to 20% U.S. and international travel required.

Salary Range: $ to $. Additional compensation may include a bonus or commission (if relevant). Additional benefits include health care, vision, dental, retirement, PTO, sick leave, etc.

Bayer is an Equal Opportunity Employer/Disabled/Veterans. Bayer is committed to providing access and reasonable accommodations in its application process for individuals with disabilities and encourages applicants with disabilities to request any needed accommodation(s) using the contact information below. Bayer is an E-Verify Employer.

Location:

United States :
Missouri :
St. Louis. Division:
Enabling Functions. Reference Code: 873561.