Software Engineer, Backend Developer

Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

Praxis Precision Medicines is building a strong pipeline of Software Engineering talent to support the continued evolution of our eDiary and clinical data platforms. Engineers in this role will first contribute to and grow within our eDiary ecosystem—a regulated, patient-facing platform used across our Epilepsy portfolio. Our engineers work across modern web and mobile applications, secure clinical data platforms, cloud infrastructure, distributed system architectures, API design, auditability frameworks, identity and access control systems, and production observability.

When you apply to this position, your profile will be considered for current and future Software Engineer openings supporting the eDiary platform and adjacent clinical systems.

• Design, develop, andmaintainreliable, production-grade code across frontend, backend, and data layers, implementing software solutions that meet clinical, operational, and regulatory requirements
• Deploy andoperateservices in a cloud environment (AWS preferred) and contribute to architecture and design reviews with a focus on reliability, scalability, and security
• Debug and resolve production issues across distributed and asynchronous workflows; diagnose performance bottlenecks; and own incident response, including root cause analysis and durable fixes that prevent recurrence
• Collaborate with QA, Clinical Operations, Clinical Development, Product, and IT stakeholders to translate requirements into validated releases
• Design APIs and data models that preserve audit trails, version history, and system traceability; and improve system observability through structured logging, monitoring, and alerting
• Uphold high standards for data integrity, security, and regulatory compliance across all systems

• Bachelor’s degree in Software
  
  Engineeringorequivalent practical experience
• 3+ years of non-internship professional software development experience, with demonstratedability to design, build, andoperateproduction software systems end-to-end
• Demonstrated experience using AI-assisted development tools (e.g., code generation, automated testing, debugging copilots) to improve engineering productivity and code quality, with ability to critically evaluate AI-generated outputs for correctness, security, and maintainability
• Strong foundation in software engineering fundamentals: data structures and algorithms, API and interface design, relational data modeling and transactional integrity, and separation of concerns
• Demonstrated ability to debug complex issues across multiple layers (client, API, database, infrastructure) and trace issues in distributed or asynchronous systems using logs, metrics, and instrumentation
• Experience deploying and operating applications in a cloud environment (any major provider), including networking, access control, configuration, and monitoring; and experience designing secure systems including authentication and authorization flows
• Experience implementing production-grade monitoring, alerting, and CI/CD practices; and ability to work effectively in a remote-first, high-accountability environment
• The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement.
  
  You’llneed comfort with screen work, basic hand coordination, and focus.
  
  Reasonableaccommodationsmay be made to enable individuals with disabilities to perform these functions.

Annualized Base Salary $105,000 — $125,000 USD

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders.

Our core Values of Trust
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