Associate Scientist, Downstream Process Development and Manufacturing

Dren Bio (the "Company") is a privately held, clinical stage biopharmaceutical company focused on developing therapeutic antibodies for the treatment of cancer, autoimmune andother serious diseases. The Company's management team and scientific advisors have profound expertise covering the discovery and development of specially engineered antibodies. Dren Bio's pipeline encompasses a multitude of programs from its two distinct, wholly-owned technologies. The Company's lead development candidate, DR-01, induces antibody-mediated killing of a specific cell type known to play a key role in various hematologic malignancies and autoimmune disorders.

In addition to DR-01, the Company has launched multiple programs from its proprietary Targeted Myeloid Engager and Phagocytosis Platform, a bispecific antibody-based technology that offers a novel mechanism of action focused on selectively engaging myeloid cells (antigen presenting cells) for the targeted depletion of pathologiccells and other disease-causing agents.

Purification Process Development and Manufacturing

Associate Scientist (Contract)

Director, Downstream Process Development

Dren Bio is seeking a highly motivated Associate Scientist to become an integral member ofthe Downstream Process Development group. The Downstream Process Development group is responsible for critical drug development functions such as: development of robust downstream processes, technology transfer and scale-up to contract manufacturing facilities,and technical support and overseeing of manufacturing at contract manufacturing facilities.

The scope of the position and requirements are described below.

Develop and scale-up robust multi-step purification processes

Timely documentation of experiments into lab notebooks

Present experimental data in project and group meetings

Author technical reports

Implement new purification technologies to optimize and streamline processes

Transfer and oversee purification process at CMO for GMP manufacturing

Review executed batch records from CMO manufacturing

Produce material for in-house development

Bachelors or Masters degree in Chemistry, Biochemistry or related scientific field.

4+ years of relevant industry experience for MS and 6+ years for BS level candidates.

Experienced in protein purification techniques including column chromatography,standard membrane filtration and Ultrafiltration/Diafiltration

Working knowledge of AKTA systems and Unicorn programming

Ability to analyze and interpret complexed process data

Work independently and proactively with minimal supervision

Strong interpersonal skills and excellent oral and written communication skills

Ability to travel and perform Person-in-Plant manufacturing oversight at a CMO is preferred

Experience working with external manufacturing vendors and partners is preferred

Dren Bio is an equal opportunity employer. Employment decisions are based on merit and business needs. Dren Bio will not discriminate against any job applicant because of race,color, national origin, ancestry, gender, sexual orientation, age, religion, creed, physicalor mental disability, gender identity, medical condition, pregnancy, marital status, veteran status, or any other characteristic protected by federal, state or local law.

Please send resume and cover letter to