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Technical Project Manager

Job in San Carlos, San Mateo County, California, 94071, USA
Listing for: Nautilus Biotechnology
Full Time position
Listed on 2026-02-16
Job specializations:
  • IT/Tech
    IT Project Manager
Salary/Wage Range or Industry Benchmark: 164000 - 221000 USD Yearly USD 164000.00 221000.00 YEAR
Job Description & How to Apply Below

At Nautilus, we have a big and important mission: to improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight.

To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines.

Responsibilities & Expectations
  • Lead medium to large scale projects for the development of the Nautilus platform including; new assays, consumables, software, and hardware. Ability to manage multiple projects simultaneously while understanding their dependencies.
  • Define project scope, objectives, and quarterly goals in alignment with high-level company and program goals. Measure and report project status using standard project management dashboards, tools, and techniques
  • Develop project plans, milestones, and deliverables from initial product conception to product release. Experience in synthesizing a diverse set of ideas into a cohesive plan that team leads will own.
  • Create and manage detailed project schedules. Work with team leads to adopt schedule management strategies.
  • Collaborate with technical leads and subject matter experts to translate technical risks and experimental outlines into actionable plans with measurable metrics. Help connect technical areas and dependencies between teams.
  • Identify and mitigate project risks and issues to remove obstacles and ensure milestone delivery on tight timelines
  • Facilitate prioritization and tradeoff decisions with teams and stakeholders
  • Effectively communicate and present project status to senior management and stakeholders
  • Display deep understanding and knowledge of Nautilus technology
  • Aid in identifying key technical resource gaps; work with functional managers to address resourcing issues
  • Utilize common Project Management tools and techniques (such as Smartsheets, Jira, and Excel) to develop appropriate processes with teams.
  • Prepare agendas, lead meetings, and distribute meeting minutes and action items
Requirements
  • This position is onsite in San Carlos, CA. This role is expected to work onsite 5 days a week during normal business hours.
  • 5-10% travel may be required.
  • Minimum of 8 years of relevant experience in Project Management with a focus on Product Development at a Biotechnology or Life Science organization is required
  • Technical expertise in a cross-functional project integrating life sciences, software, hardware, assay, and consumables
  • Experience taking a product from concept to successful commercial launch
  • Experience at an early stage start-up
  • Bachelor's degree in biology or chemistry (or a closely related field) is required. Master's or PhD strongly preferred.
  • PMP Certification, SAFe or equivalent Agile Certifications preferred
Nautilus Team Culture
  • We are determined to do whatever it takes to get our platform into the hands of researchers who will use it to upend the status quo in basic research and healthcare.
  • We work on cross functional teams, wear many hats, take risks to work through uncertainty, enjoy working collaboratively on challenging problems, and celebrate one another’s victories.
  • We go above and beyond, but also strive to provide a supportive atmosphere of colleagues who are willing to lend a helping hand and make working at Nautilus not only fulfilling in its end goals, but enjoyable on a day-to-day basis.

Compensation Range: $164K - $221K

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