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Scientist ; Contractor-Analytical Development-Characterization

Job in San Carlos, San Mateo County, California, 94071, USA
Listing for: Vaxcyte Inc
Contract position
Listed on 2026-06-26
Job specializations:
  • Research/Development
    Research Scientist, Biotech Research, Pharmaceutical Science/ Research
Salary/Wage Range or Industry Benchmark: 80000 - 100000 USD Yearly USD 80000.00 100000.00 YEAR
Job Description & How to Apply Below
Position: Scientist I (Contractor)-Analytical Development-Characterization

Scientist I (Contract), Analytical Development

Summary

We are seeking a highly motivated Scientist to join our analytical development team. In this role, you will play a key part in advancing complex vaccines by applying cutting‑edge analytical techniques. This position offers the opportunity to take ownership of method development, contribute to impactful projects, and collaborate closely with cross‑functional teams in a fast‑paced, science‑driven environment. The ideal candidate will embody and uphold our core values of rethinking convention, aiming high, leading with heart, and modeling excellence in all aspects of their work.

Essential

Functions

Independently design and execute experiments to support analytical characterization of proteins, drug substances, and conjugates.

Develop and optimize HPLC‑based separation methods (e.g., AEX, SEC, SEC‑MALS) to address complex analytical challenges.

Design and implement mass spectrometry‑based workflows for detailed molecular characterization.

Analyze and interpret complex datasets and drive solutions forward.

Maintain accurate and detailed records using an electronic laboratory notebook (ELN).

Collaborate with cross‑functional partners to support project goals and deliver high‑quality analytical data.

Communicate findings clearly through presentations and discussions, contributing to team learning and decision‑making.

Qualifications
  • PhD, MS or Bachelor’s degree in Chemistry, Biochemistry, Biology, Pharmaceutical Sciences, or a related scientific discipline. PhD with 1‑2 years; MS with 5+ years; BS with 8+ years of relevant industry experience in analytical development, QC, or related field. Other combinations of education and/or experience may be considered.
  • Proven experience in HPLC method development and optimization, particularly AEX, SEC, and SEC‑MALS.
  • Strong understanding of chromatographic principles and their application to biomolecular analysis.
  • Working knowledge or experience with NMR spectroscopy is highly desirable.
  • Hands‑on experience with LC‑MS, including peptide mapping and intact mass analysis.
  • Familiarity with mass spectrometry platforms such as Orbitrap, Q‑TOF, or triple quadrupole.
  • Strong analytical thinking skills and the ability to troubleshoot complex problems independently.
  • Detail‑oriented with excellent documentation and organizational skills.
  • Effective communicator and collaborative team player.
  • Eager to learn, adaptable, and excited to contribute to a dynamic and innovative environment.
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