Software Engineer, Full Stack - Early Cancer Detection; ECD

Position Summary

We are seeking an experienced Staff Software Engineer, Backend (or Full Stack), for our Early Cancer Detection (ECD) program, who excels at collaboratively solving complex problems. If you take ownership of your work, think strategically, and have a proven track record of implementing solutions while adapting to constraints and minimizing risks, we encourage you to apply. Strong technical expertise, excellent communication skills, and a desire to thrive in a dynamic environment are essential.

In this role, you will collaborate closely with our Engineering Team, Product Managers, and Designers to develop innovative experiences for our internal stakeholders, primarily focusing on creating a custom lab software solution for a high‑throughput laboratory.

• Design, develop, and maintain scalable services that support the diverse activities of a high‑throughput laboratory.
• Develop back‑end applications that interact with other software.
• Implement and manage CI/CD pipelines using Git Lab.
• Develop comprehensive tests (unit, API, integration) to ensure high code quality.
• Collaborate closely with end‑users and product managers to iterate on requirements and deliverables.
• Optimize architecture and infrastructure on the AWS cloud platform for performance, scalability, reliability, and cost‑effectiveness.
• Proactively monitor system performance, troubleshoot issues, conduct thorough root cause analysis, and implement enhancements to improve efficiency and reliability.
• Stay current with emerging technologies and best practices in software engineering and actively contribute to continuous improvement initiatives.
• Be the technical lead and mentor more junior engineers.

• BS degree in computer science, comparable program, or equivalent.
• 10+ years of full stack software development experience.
• Proven experience with programming languages such as Type Script (preferred), or Python.
• Experience with software development lifecycle process from build, software configuration, change control, and release and deployment activities.
• Strong quality assurance mindset with a commitment to delivering robust and reliable software.
• Proficiency in messaging frameworks such as Kafka.
• Proficiency in infrastructure as code (IaC).
• Excellent problem‑solving skills and the ability to work both independently and collaboratively in a dynamic environment.
• Excellent use of modern agent‑driven development practices.
• Strong written and verbal communication skills, coupled with excellent interpersonal skills enabling effective interaction with stakeholders at all levels.

• Experience working in highly regulated environments.
• Able to visit the lab in San Carlos, CA on a regular basis to facilitate direct observation of the software in the lab and obtain real‑time user feedback.

This range reflects a good‑faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.

• Annual performance incentive bonus
• Long‑term equity awards
• Comprehensive health benefits (medical, dental, vision)
• 401(k) with company match
• Generous paid time off and company holidays
• Additional wellness and work‑life benefits

Compensation Range: $167,300—$209,100 USD

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.