Accounting Manager; Temporary

Description

* This is a 9 to 10 month temporary in-person position, with an expectation of 5 days in-office per week.*

Vividion is a next generation biotechnology company based in San Diego that is leveraging its proprietary chemical proteomics platform to conduct proteome-wide foot printing of drug-protein interactions with unprecedented breadth and precision. Our technology allows us to screen, identify and optimize novel drugs that selectively bind virtually any protein, including proteins previously considered “undruggable”. Our pipeline and emerging programs reflect a matured and productive platform capable of delivering first in class drugs utilizing novel mechanisms of action (allosteric inhibitors, protein-protein interaction inhibitors, functional activators, degraders etc.)

against undruggable targets in the oncology and immunology space.

We prize scientific excellence, creativity, team players and we are committed to continued innovation. We have worked hard to create a collaborative and dynamic work culture where your ideas and discoveries are valued and will have an impact. We are growing and there are opportunities for mentorship and career progression.

Vividion has been recognized as a Top Workplace by The San Diego Union-Tribune from 2022 to 2025.

Vividion Therapeutics, Inc. is seeking an experienced Accounting Manager to provide temporary backfill for an established Accounting Manager position during a defined period in 2026. Reporting to the Controller, this role will support a high-growth biotechnology environment by maintaining continuity across core monthly close responsibilities and advancing two defined 2026 accounting initiatives.

This is a hands-on Accounting Manager role that owns core general ledger responsibilities, with a primary focus on monthly close execution and nonclinical and preclinical accounting. The role requires a senior accounting professional who can assume ownership of in-flight work, operate within established processes and controls, and deliver accurate, timely results with minimal ramp time.

While the primary focus is execution and continuity, practical efficiencies identified through day-to-day ownership may be implemented where appropriate and aligned with existing frameworks. Success in this role will be measured by maintaining close quality and timelines, ensuring progress on defined initiatives without disruption, and providing clear documentation and handoff at the conclusion of the assignment.

• Own accounting for nonclinical and preclinical activities, including progress to completion methodologies, accrual models, and project level reporting cadence.
• Prepare, maintain, and standardize complex accounting schedules; review staff prepared models for accuracy, scalability, and audit readiness.
• Own methodologies, controls, and supporting documentation for vendor prepayments, ensuring proper recognition and reconciliation.

• Own month end close activities for assigned areas, including journal entry preparation, reconciliations, and close related analyses.
• Review nonclinical and preclinical schedules and entries to ensure completeness, accuracy, and appropriate application of accounting judgment.
• Drive timely, well controlled close cycles through proactive issue identification, disciplined execution, and effective cross functional coordination.

• Lead accounting participation in the ongoing ERP implementation, including requirements definition, data mapping, data conversion, UAT, reporting validation, and post go live stabilization—ensuring decisions preserve and improve monthly close ownership for the function long term.
• Execute assigned accounting work streams and partner with cross functional stakeholders on system design decisions impacting controls, workflows, and reporting outcomes.

• Own record to report fixed asset accounting, including asset additions, disposals, transfers, impairments, and depreciation.
• Maintain and reconcile the fixed asset subledger, ensuring accuracy, completeness, and alignment with general ledger balances.
• Lead the completion of the company’s fixed asset inventory, building on work already underway, by designing final audit procedures, defining documentation standards, and coordinating execution in partnership with the Facilities team.
• Review inventory results, investigate and resolve discrepancies, and ensure appropriate capitalization, retirement, or impairment treatment.
• Prepare and maintain fixed asset schedules, policies, and audit ready documentation.

• Prepare variance analyses and financial reporting packages, providing insight into key drivers, risks, and process performance.
• Identify and implement opportunities for process improvement, automation, and…