Senior Manager, Biostatistics

Overview

At Rayze Bio, every day is an opportunity to ignite meaningful change. As a wholly‑owned subsidiary of Bristol Myers Squibb, we blend a nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. From day one, you will make an immediate impact on our science, teams, and patients.

Senior Manager, Biostatistics

• Serve as the study biostatistician for assigned clinical oncology studies, contributing to development and execution of statistical strategies, study designs, and analyses.
• Collaborate closely with multidisciplinary project teams to ensure timely communication and alignment of objectives.
• Identify and implement solutions to statistical and data analysis issues related to clinical trials and regulatory submissions.
• Author and contribute to key statistical documents and outputs, including protocol statistical sections, Statistical Analysis Plans (SAPs), and Table‑Line‑Figure (TLF) shells, with review by senior biostatisticians.
• Review study‑related documents and validate vendor deliverables, including CDISC data specifications and TLF/analysis outputs.
• Work with internal programmers to support regulatory requests, DSUR/IB updates, and ad‑hoc analyses as needed.
• Participate in the internal sponsor review of ongoing clinical data.
• Support AI initiatives led by the Biometrics AI lead that enhance quality control and operational efficiency.

• Advanced degree in Statistics or Biostatistics (PhD or MS).
• 3+ years (PhD) or 6+ years (MS) of biostatistics experience in the pharmaceutical/biotech industry.
• Proficiency with statistical programming tools (SAS and/or R) and working knowledge of CDISC standards (SDTM/ADaM).
• Strong interpersonal, communication, and collaboration skills for cross‑functional stakeholders.
• Ability to work on site in our San Diego Office with a hybrid work schedule; willingness to travel ≈10% and work evenings/weekends.
• Experience working with vendors to ensure quality, timeliness, and compliance of biometrics deliverables.
• Solid understanding of GCP, ICH guidelines, regulatory requirements, and good SOP compliance.
• Working knowledge of Bayesian methods and exposure to innovative/novel clinical trial designs (e.g., adaptive designs).
• Familiarity with AI‑enabled tools to improve productivity and work efficiency.
• Preferred:
  Prior experience in oncology clinical development.

$164,846–$199,754 (full‑time)

• Health Coverage:
  Medical, pharmacy, dental, and vision care.
• Well‑being Support:
  Employee Assistance Programs and well‑being accounts.
• Financial Protection: 401(k) plan, disability, life insurance, and supplemental health insurance.
• Paid Time Off:
  Flexible time off, unlimited paid time off with manager approval, national holidays.
• Additional Benefits:
  Short‑ and long‑term disability, business travel protection, personal liability protection, identity‑theft benefit, and more.

Rayze Bio is an equal opportunity employer committed to a diverse workforce. We provide a transparent recruitment process and reasonable workplace accommodations for qualified applicants with disabilities. We consider applicants with arrest and conviction records in accordance with applicable laws.

We do not request payments, financial information, or social security numbers during our application or recruitment process. All data processed in connection with role applications will be treated in accordance with applicable privacy policies and regulations.