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Senior Systems Engineer, IT Infrastructure & Cloud Solutions

Job in San Diego, San Diego County, California, 92189, USA
Listing for: Neurocrine Biosciences
Full Time position
Listed on 2026-08-30
Job specializations:
  • IT/Tech
    Cybersecurity, Systems Engineer
Salary/Wage Range or Industry Benchmark: 103300 - 141000 USD Yearly USD 103300.00 141000.00 YEAR
Job Description & How to Apply Below

Who We Are:

Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis
* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science.

For more information, visit , and follow the company on Linked In, X, Facebook and You Tube. (
* in collaboration with Abb Vie)

About the Role

This is a hands‑on, automation‑driven senior systems security engineering role responsible for planning, implementing, and driving enterprise technology infrastructure security posture and regulatory compliance readiness across Linux, Windows, cloud, on‑prem, and hybrid environments. The engineer serves as a senior technical resource for enterprise infrastructure vulnerability management, overseeing the process from initial alert through remediation and closure verification. The role also develops and improves patch automation using scripting, configuration management, and orchestration, while continuously evaluating tools and processes to adapt to changes in the infrastructure and threat landscape.

The engineer applies deep systems engineering and enterprise systems administration expertise to plan and execute security patches, and translates Cybersecurity policy requirements into implemented, auditable controls, establishing KPIs to measure and report progress against security risk remediation goals. The engineer also establishes and maintains Standard Operating Procedures (SOPs) and change management controls to ensure infrastructure security changes are consistently documented and traceable.

This provides objective evidence for security and access control audits while maintaining continuous organizational audit readiness. This role serves as a key technical resource and liaison between Cybersecurity, IT business partners, Internal Audit, and Compliance/Quality functions, ensuring that security requirements are operationalized consistently and remediation work is tracked to closure with measurable outcomes.

Your Contributions (include, but are not limited to)
  • Security Automation and Vulnerability Management at Scale
  • Lead complex infrastructure vulnerability remediation efforts and continuously improve the tools and automation used to detect, remediate, and verify security findings across Linux, Windows, cloud, network, and hybrid infrastructure
  • Plan and implement security patches across enterprise Linux and Windows server environments, including patch testing, sequencing, rollback planning, and post patch validation
  • Lead and coordinate the enterprise vulnerability remediation program across cloud (AWS/Azure), on prem, and hybrid infrastructure, prioritizing based on risk severity, exploitability, and business impact
  • Design and implement a scalable patch management framework across AWS, Azure, and hybrid infrastructure including Linux and Windows servers, network devices, and platform services, reducing reliance on manual, one‑off remediation efforts
  • Apply enterprise systems administration expertise (OS hardening, configuration management, service dependencies) to assess patch impact and minimize disruption to production systems
  • Partner with Cybersecurity to translate vulnerability scan findings and audit action items into clear, actionable remediation plans with committed timelines and owners
  • Extend vulnerability management support to the application layer,…
Position Requirements
10+ Years work experience
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