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Enterprise Architect Director

Job in San Diego, San Diego County, California, 92189, USA
Listing for: Neurocrine Biosciences
Full Time position
Listed on 2026-10-05
Job specializations:
  • IT/Tech
    Systems Engineer, Data Engineering, Information Security & Data Protection
Salary/Wage Range or Industry Benchmark: 195700 - 267000 USD Yearly USD 195700.00 267000.00 YEAR
Job Description & How to Apply Below
Who We Are:

Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis
* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science.

For more information, visit , and follow the company on Linked In, X, Facebook and You Tube. (
* in collaboration with Abb Vie)

About the Role:

The Director, IT – Enterprise Architect serves as the enterprise architecture thought leader and provides strategic leadership for the enterprise architecture practice, defining the target-state architecture, standards, and multi-year technology roadmap that align IT investment with enterprise strategy. This role partners with business and IT leaders across research, drug development, manufacturing, quality, commercial, and G&A to translate business capability needs into scalable, compliant, and cost-effective solution architectures.

The Director establishes the architecture governance model that guides enterprise technology and architecture decisions in validated and non-validated environments.

Your Contributions (include, but are not limited to):

Define and drive the enterprise architecture vision, current and target-state architecture, and multi-year technology roadmap aligned to enterprise business strategy, Translating strategic business priorities into actionable technology direction and investment priorities Establish, evolve and drive adoption of enterprise architecture frameworks, reference architectures, design principles, and architecture standards that enable consistent enterprise technology decisions Lead the architecture governance process, including design authority forums, architecture review boards, and exception management Conduct business capability assessments and capability-to-application mapping to identify gaps, redundancies, and investment priorities Provide strategic architecture direction and expert guidance for end-to-end solutions across core enterprise platforms, including ERP, CRM, PLM, SCM, quality, laboratory, and financial systems Define and influence enterprise-wide integration and API strategy, including middleware standards and B2B integration approaches Define the enterprise data and analytics architecture direction and standards, covering data platforms, data domains, governance, and consumption patterns, in partnership with relevant functional experts Establish and influence enterprise cloud, security, and AI architecture patterns in partnership with Infrastructure, Information Security, and Data Engineering functions Ensure architecture designs satisfy GxP, data integrity, privacy, and computer system validation requirements, including 21 CFR Part 11 and GAMP 5 expectations, on a case-by-case basis Provide strategic architecture leadership on M&A, divestiture, and in-licensing activity, including system integration, separation, and transition planning Partner with sourcing and vendor management on technology…

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