Controlled Environment Agriculture; CEA) Production Supervisor Job San Diego area,California USA,Manufacturing / Production

Controlled Environment Agriculture (CEA) Production Supervisor Cirsium Biosciences is an early-stage biotechnology company developing a novel plant-based platform for AAV production. We are advancing our technology from Research through Process Development and toward clinical and manufacturing readiness.

Position Summary

Function: Controlled Environment Agriculture / Production

Level: Lead/Supervisor

Position: Full-time

Reports To: Facilities Manager

Cirsium Biosciences is seeking a hands-on Controlled Environment Agriculture (CEA) Production Supervisor to lead daily plant production activities within our indoor hydroponic biopharmaceutical production operation. This position is responsible for organizing and executing production workflows, supervising and training CEA Production Associates, maintaining accurate production records, and monitoring plant health and crop performance.

This is an onsite, boots-on-the-ground supervisory role. The successful candidate will work directly in controlled growing and production areas, coordinate people, materials, equipment, and schedules, and ensure work is performed safely, consistently, and in accordance with approved procedures, batch records, and work instructions.

The ideal candidate combines practical commercial growing experience with strong frontline leadership and the ability to recognize plant-health, environmental, operational, and contamination risks early. The role requires disciplined execution, accurate documentation, sound judgment, and effective collaboration with Quality, Process Development, Facilities, Materials, and other supporting functions.

Key responsibilities

CEA Production Execution and Scheduling

Lead daily CEA production activities, including plug preparation, sowing, germination, transplanting, crop maintenance, irrigation and nutrient dosing, vacuum infiltration, harvesting, material movement, and production‑area cleaning.
Organize labor, materials, equipment, and production areas to execute scheduled production activities safely, consistently, and on time.
Run production workflows directly when needed and maintain a hands‑on presence in CEA operations.
Ensure work is completed in the correct sequence and according to approved procedures, batch records, work instructions, production schedules, and established process requirements.
Coordinate daily production priorities and identify schedule risks, staffing constraints, material shortages, equipment limitations, or other issues that may affect planned work.
Confirm production readiness before scheduled activities, including personnel availability and training, required materials, equipment status, documentation, and production‑area readiness.

Plant Health and Crop Performance

Monitor plant health, growth, uniformity, and crop performance throughout the production lifecycle and identify abnormal trends or conditions requiring escalation.
Conduct routine crop scouting and identify early signs of plant stress, irrigation or nutrient issues, pests, disease, suspected pathogens, or environmental variation.
Monitor and document relevant growing conditions, including temperature, relative humidity, light, carbon dioxide, irrigation, nutrient solution, pH, and electrical conductivity.
Document plant-health observations, crop losses, and abnormal conditions accurately and promptly, and elevate potential pathogen, pest, environmental, or process‑related concerns.
Investigate plant‑health trends and crop losses in collaboration with Quality, Process Development, and other appropriate functions and support implementation of approved corrective and preventive measures.
Track crop‑performance trends and communicate observations that may affect production consistency, yield, process development, or…