Program Manager, Preclinical Programs

Who We Are:

Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life‑changing treatments for patients with under‑addressed neurological, psychiatric, endocrine and immunological disorders. The company’s diverse portfolio includes FDA‑approved treatments for tardive dyskinesia, chorea associated with Huntington’s disease, classic congenital adrenal hyperplasia, hyperphagia in Prader‑Willi syndrome, endometriosis
* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid‑to‑late‑phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science.

For more information, visit , and follow the company on Linked In, X, Facebook and You Tube. (
* in collaboration with Abb Vie)

The Program Manager role supports the planning, execution, and operational effectiveness of Preclinical programs and initiatives. Provides program management leadership across multiple Preclinical functional sub teams, partnering with scientific and functional leads to translate cross‑functional program strategies into integrated plans and coordinated execution spanning early research through Development Candidate selection, IND/CTA readiness, and First‑in‑Human development. The Program Manager partners closely with subject matter experts across Toxicology, DMPK/ADME, Bioanalytical Sciences, Clinical Pharmacology, Clinical Pharmacology Bioanalytical, and Pharmacometrics, and interacts with stakeholders across Research, CMC, Clinical Development, Regulatory Affairs, Finance, and Program Management to facilitate alignment on program strategy, milestones, risks, timelines, resources, and critical‑path activities.

The role also supports broader early‑development portfolio visibility, ensuring that emerging program information, risks, dependencies, and decisions are appropriately communicated across functional, asset, portfolio, and leadership governance forums.

• Provides program management leadership for 6 or more Preclinical functional sub teams representing defined segments of the preclinical portfolio and partners with scientific leads and subject matter experts to coordinate execution across multiple assets and development stages.
• Facilitates team alignment and execution against integrated program plans, including management of key milestones, dependencies, risks/issues, critical‑path activities, budgets, resources, and governance requirements from early development through IND/CTA and FIH readiness.
• Partners with subject matter experts across Toxicology, DMPK/ADME, Bioanalytical, Clinical Pharmacology, Clinical Pharmacology Bioanalytical, and Pharmacometrics to integrate functional plans, identify cross‑disciplinary dependencies, and proactively surface risks or decisions that may affect program timelines.
• Develops and maintains integrated project plans, timelines, risk and action trackers, meeting documentation, dashboards, and program status updates.
• Monitors program performance and facilitates issue resolution and appropriate escalation to maintain progress toward development objectives.
• Supports preparation for key portfolio and development milestones, including Portfolio Entry, Development Candidate selection, IND/CTA readiness, and First‑in‑Human activities, ensuring appropriate functional planning and visibility ahead of major decision points.
• Partners with the designated Preclinical Representative to support effective representation of the integrated Preclinical perspective within cross‑functional Asset/Core Teams, ensuring that relevant scientific considerations, functional risks, dependencies, and recommendations are appropriately aligned and communicated.
• Partners with Cross‑Functional Program Management, CMC Functional Program…