Postdoctoral Associate - Droujinine Lab - Molecular & Cellular Biology

ABOUT US

Scripps Research is a nonprofit biomedical institute ranked as one of the most influential in the world for its impact on innovation. We celebrated our 100‑year legacy in 2024. This significant milestone marks a century of seminal discoveries in immunology, infectious diseases (such as COVID‑19, flu, HIV), neuroscience, heart disease, cancer, and more. Located in La Jolla, California, the institute houses six research departments, multiple Nobel laureates, a top‑ranked graduate school, and a leading postdoctoral training program.

Scripps Research encompasses two elite and highly innovative institutes, the Cali ‑Skaggs Institute for Innovative Medicines and Scripps Research Translational Institute, which merge foundational studies in biology, chemistry, and computer science with translational science to produce pioneering drugs and advances in digital and precision medicine. Together, we cultivate new scientific leaders and expand the frontiers of knowledge to deliver medical breakthroughs impacting human health around the globe.

If you have a passion for making a difference, this could be your opportunity to join our transformative team.

Postdoctoral Associate

We are seeking a highly motivated Postdoctoral Associate. The ideal candidate will lead their own project and perform mammalian cell culture, in vivo mouse experiments, in vivo genetic screens, quantitative TMT mass spectrometry proteomics, metabolomics, western blot, pulldowns, DNA cloning, immunostaining, confocal microscopy, high‑throughput screens, and bioinformatic data analysis. Significant emphasis is placed on the professional development of the Postdoctoral Associate.

More information on the project will be discussed during the interview process.

To maintain homeostasis, organisms rely on internal signaling networks that orchestrate the physiological response across different tissues and organs. Intriguingly, perturbation in one tissue elicits secreted signals that transmit the information to other tissues and these signals are important for maintenance of health and longevity. Secreted proteins are key components of interorgan signaling that coordinate organ functions by signaling over long distances.

Destabilization of these interorgan signaling networks, responsible for the orchestration of physiological responses across organs, drives age‑associated disease, including diabetes, cancer, or chronic inflammation. Despite this, the composition and activity of interorgan communication networks and their impact on aging and disease remain poorly defined. The Droujinine Lab has developed novel methods to identify and characterize novel secreted factors that coordinate organ functions in homeostasis and disease in mammalian systems.

Specifically, we use proteomics and in vivo functional genomic screens to uncover the secreted proteins and cellular circuitry involved in homeostasis, obesity, and aging. To learn more please visit www.scripps.edu/droujinine.

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• PhD degree in biology, physiology, neuroscience, chemical biology, biological engineering, or related discipline. Candidates who are about to defend their thesis are welcome to apply.
• Experience in biologic techniques outlined in the position summary highly preferred but not required.
• High motivation and independence in reading scientific literature and performing experiments.

This position works in a laboratory or vivarium environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.

Postdoctoral Associates will be hired following the National Institute of Health and California's exempt salary guidelines, which provide for a starting range of $68,640–$73,230. Consideration will be given to experience that exceeds the listed requirements.

• Eligibility for retirement plans with employer contribution.
• Full suite of Health and Welfare plans including three medical plan options (including an HSA available option), dental, vision, life…