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Scientist, Immunology Discovery

Job in San Diego, San Diego County, California, 92189, USA
Listing for: Merck & Co.
Full Time position
Listed on 2026-07-23
Job specializations:
  • Research/Development
    Immunology Research, Research Scientist, Biotech Research, Drug Discovery
Salary/Wage Range or Industry Benchmark: 87300 - 137400 USD Yearly USD 87300.00 137400.00 YEAR
Job Description & How to Apply Below

Overview

Our Company is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Our company's Research Labs San Diego is committed to bringing life‑changing therapies to patients in need. With a patient‑focused approach harnessing cutting‑edge precision medicine, it is our mission to transform the landscape of inflammatory and autoimmune diseases. Immunology Discovery leads and supports our company's pipeline programs encompassing early target discovery and validation, drug discovery, and translational sciences, including bioinformatics, chemical biology, antibody discovery, and clinical development.

Responsibilities
  • Work independently and as part of a team to support the early development of novel therapeutics for inflammatory and autoimmune diseases.
  • Design and perform cell‑based functional assays (cell lines, primary cells) and biochemical assays with a wide range of methodologies to support target validation, antibody drug screening, mechanism of action studies, biomarker identification in the preclinical and IND‑enabling space.
  • Analyze, critically interpret data, and utilize findings for assay development and optimization.
  • Keep meticulous records of experiments performed, maintain lab notebook entries, and share results with project teams as required.
  • Collaborate closely with members within the department and across functional teams in support of research projects/programs at different stages.
Qualifications Education
  • Bachelor's (with 3+ years) or Master's in Biology, Biochemistry, or related life sciences field with relevant experience
Required Experience and Skills
  • Strong cell culture skills including mammalian cell lines and human primary cells (PBMCs).
  • Experience developing ex‑vivo cell‑based assays to assess immune responses from primary cells or cell lines.
  • Proficiency in optimizing and executing immunoassays (Meso Scale Discovery, ELISA, others) to measure analytes in serum, plasma, supernatant or cell lysates.
  • Experience in multi‑color flow cytometry to immunophenotype human cells to assess immune response or cell signaling pathways.
  • Strong data analytical and problem‑solving skills, with proficiency in standard scientific software used for data analysis (Excel, Prism (Graph Pad), Flow Jo).
  • Excellent oral and written communication skills, with the ability to function and communicate effectively in a multi‑disciplinary environment and thrive in a team environment.
Preferred Experience and Skills
  • Experience in spectral flow cytometry.
  • Experience with molecular/ cell biology techniques such as CRISPR, RT‑PCR, cell transfection, cell line generation.
  • Basic understanding of immunology.
  • Understanding of the drug discovery process with prior industry experience.
Salary

$87,300.00 - $

Benefits

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at

EEO Statement

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.

For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights; EEOC GINA Supplement. We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds and skills come together in an inclusive environment.

We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

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