Senior Research Associate, Pharmacology; Contractor

Job Title

The successful candidate will provide in vivo and ex vivo support for pre-clinical drug development and discovery efforts for treating inflammatory and autoimmune diseases.

The role requires independent study execution, mechanistic investigation, data analysis, and effective communication of scientific findings within cross-functional project teams.

• Independently design, plan, and execute in vivo experiments; conduct follow on ex vivo analysis addressing drug mechanism-of-action.
• Execute pharmacokinetic / pharmacodynamic, target engagement, efficacy, or mechanism of action studies to support pre-clinical and discovery programs.
• Administer small molecule compounds to mice, measure endpoints (e.g., body/tissue weight) and collect blood/tissue for analysis.
• Perform ex vivo analysis on collected sera and/or tissues as required. Assays include and not limited to: MSD, ELISA, multiplex Immunoassay (Legend Plex), flow cytometry, and qPCR.
• Analyze, interpret, and visualize experimental data (Prism, Excel) and other data analysis tools and maintain accurate experimental records and organize scientific data in a clear and reproducible manner.
• Work both independently and collaboratively within a multidisciplinary pharmacology team.
• Collect, organize and present scientific/technical data (PowerPoint) internally and in project team meetings.

• BS with 6+ years' experience of in vivo in a biotechnology or pharmaceutical setting. Ideally the degree should be in Biology, Immunology, Pharmacology, or related field. Preference given to Immunology experience.
• Rodent dosing routes (PO, IV, IP, SC), blood collection (sub-mandibular, terminal cardiac), necropsy, and organ collection are required.
• Experience with the following techniques is highly desired: flow cytometry, qPCR, MSD, Luminex, and ELISA.
• Rodent surgery experience is a plus.

• Effective troubleshooting and problem-solving skills.
• Excellent oral and written communication skills.
• Be an effective team player and strong individual contributor, flexible, and able to handle multiple tasks and deliver high-quality results under tight timelines.

The hourly pay for this position ranges from $38.00 to $45.00 depending on relevant skills, experience, and education.

Vividion Therapeutics, Inc. is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other characteristic protected by applicable federal, state, or local laws.